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  1. Article

    Open Access

    A deep learning system for predicting time to progression of diabetic retinopathy

    Diabetic retinopathy (DR) is the leading cause of preventable blindness worldwide. The risk of DR progression is highly variable among different individuals, making it difficult to predict risk and personalize...

    Ling Dai, Bin Sheng, Tingli Chen, Qiang Wu, Ruhan Liu, Chun Cai in Nature Medicine (2024)

  2. Article

    Open Access

    Clinical value of folate receptor-positive circulating tumor cells in patients with esophageal squamous cell carcinomas: a retrospective study

    The aim of the study is to explore the role of preoperative folate receptor-positive circulating tumor cell (FR+CTC) levels in predicting disease-free survival (DFS) and overall survival (OS) in patients with eso...

    Qiang Zhou, Qiao He, Wenwu He, Chenghao Wang, Guangyuan Liu, Kangning Wang in BMC Cancer (2023)

  3. Article

    Open Access

    A new histone deacetylase inhibitor remodels the tumor microenvironment by deletion of polymorphonuclear myeloid-derived suppressor cells and sensitizes prostate cancer to immunotherapy

    Prostate cancer (PCa) is the most common malignancy diagnosed in men. Immune checkpoint blockade (ICB) alone showed disappointing results in PCa. It is partly due to the formation of immunosuppressive tumor mi...

    Zude Chen, **aoshuang Yang, Zugen Chen, Minzhao Li, Wei Wang, Riwei Yang in BMC Medicine (2023)

  4. Article

    Open Access

    Circular RNA CCT3 is a unique molecular marker in bladder cancer

    This study surveyed circular RNA CCT3 in bladder cancer (BCa). We recruited 85 BCa patients and 40 normal controls (Normal) and collected clinical specimens for analysis. circRNA CCT3 expression was analyzed b...

    Lin Luo, Qingzhi **e, Yunchou Wu, ** Li, FuQiang Qin, Dunming Liao in BMC Cancer (2023)

  5. Article

    Open Access

    hsa_circ_0003596, as a novel oncogene, regulates the malignant behavior of renal cell carcinoma by modulating glycolysis

    This research was planned to analyze hsa_circ_0003596 (circCOL5A1) and glycolysis-focused mechanisms in renal cell carcinoma (RCC).

    QingZhi **e, FuQiang Qin, LiHui Luo, ShaoQuan Deng in European Journal of Medical Research (2023)

  6. Article

    Open Access

    Neutralizing antibody levels associated with injectable and aerosolized Ad5-nCoV boosters and BA.2 infection

    Several COVID-19 vaccines are in widespread use in China. Few data exist on comparative immunogenicity of different COVID-19 vaccines given as booster doses. We aimed to assess neutralizing antibody levels rai...

    Fuzhen Wang, Baoying Huang, Yao Deng, Shaobai Zhang, **aoqiang Liu in BMC Medicine (2023)