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Article
The synergy of inorganic cluster cage and organic ligands in lanthanide-titanium-oxo clusters scintillators for high performance X-ray imaging
With the increasing demand for X-ray imaging, especially for three-dimensional imaging of curved and irregular objects, the development of high-performance flexible scintillation films has attracted significan...
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Article
Open AccessAdaptive responses of erythritol-producing Yarrowia lipolytica to thermal stress after evolution
Elucidation of the thermotolerance mechanism of erythritol-producing Yarrowia lipolytica is of great significance to breed robust industrial strains and reduce cost. This study aimed to breed thermotolerant Y. li...
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Article
Open AccessModular assembly of an artificially concise biocatalytic cascade for the manufacture of phenethylisoquinoline alkaloids
Plant-derived alkaloids are an important class of pharmaceuticals. However, they still rely on phytoextraction to meet their diverse market demands. Since multistep biocatalytic cascades have begun to revoluti...
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Chapter and Conference Paper
Optimization of Compensation Parameters for DC High-Voltage Power Supply Using PSO
The insulated core transformer type DC high-voltage power supply is widely used due to its advantages of high energy conversion efficiency, high output power, and low cost. However, the design and optimization...
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Article
Development of Certified Reference Materials of Trace Elements in Gold Solution (GBW02797–GBW02800)
Based on ISO 17034 and ISO Guide 35, a new series of matrix reference materials for 23 trace elements in 2 mg/mL gold solutions with five concentration levels (0, 1, 5, 10 and 20) ng/mL were developed, respect...
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Article
Open AccessFNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1
Regenerative therapy based on mesenchymal stem cells (MSCs) has great promise to achieve functional recovery in cerebral infarction patients. However, the survival rate of transplanted MSCs is extremely low be...
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Article
Brain-specific Pd1 deficiency leads to cortical neurogenesis defects and depressive-like behaviors in mice
Embryonic neurogenesis is tightly regulated by multiple factors to ensure the precise development of the cortex. Deficiency in neurogenesis may result in behavioral abnormalities. Pd1 is a well-known inhibitor...
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Article
Open AccessCombination tanning mechanism inspired environmentally benign catalyst for efficient degradation of tetracycline
The utilization of chelation reaction between metals and tannins is a common tanning method in leather chemistry. Herein, a novel combination tanning mechanism inspired environmentally benign catalyst (CMBT-Fe0) ...
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Article
Open AccessOverall survival prediction models for gynecological endometrioid adenocarcinoma with squamous differentiation (GE-ASqD) using machine-learning algorithms
The actual 5-year survival rates for Gynecological Endometrioid Adenocarcinoma with Squamous Differentiation (GE-ASqD) are rarely reported. The purpose of this study was to evaluate how histological subtypes a...
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Article
Rapid Ferroelectric-Photoexcited Bacteria-Killing of Bi4Ti3O12/Ti3C2Tx Nanofiber Membranes
In this study, an antibacterial nanofiber membrane [polyvinylidene fluoride/Bi4Ti3O12/Ti3C2Tx (PVDF/BTO/Ti3C2Tx)] is fabricated using an electrostatic spinning process, in which the self-assembled BTO/Ti3C2Tx het...
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Article
Open AccessApplication of a preoperative pain management mode based on instant messaging software in elderly hip fracture patients: a randomized controlled trial
Preoperative analgesia of hip fracture in elderly patients is important, but it is also lacking. In particular, nerve block was not provided in time. In order to provide more effective analgesia, we designed a...
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Article
Open AccessCan global or national disability weights represent provincial level?
A universal set of disability weights(DWs) is mainly based on the survey of North America, Australia and Europe, whereas the participants in Asia was limited. The debate hasn’t yet settled whether a universal ...
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Article
Neohesperidin Alleviates the Neuropathic Pain Behavior of Rats by Downregulating the P2X4 Receptor
Neuropathic pain (NP) is a type of chronic pain affecting 6–8% of human health as no effective drug exists. The purinergic 2X4 receptor (P2X4R) is involved in NP. Neohesperidin (NH) is a dihydroflavonoside com...
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Article
Biomass pretreatment method affects the physicochemical properties of biochar prepared from residues of lignocellulosic ethanol production
This work investigated the influence of pretreatment methods (using sulfuric acid, sodium hydroxide, or calcium hydroxide) on the characteristics of biochar prepared from residues generated by lignocellulosic ...
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Article
Open AccessEffect of perioperative ultrasound guided fascia iliaca compartment block in elderly adults with hip fractures undergoing arthroplasty in spinal anesthesia—a randomized controlled trial
For elderly adults undergoing hip arthroplasty, fascia iliaca compartment block (FICB) is often used before spinal anesthesia to reduce the pain of posture placement. However, the impact of FICB within 48 h ne...
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Article
Open AccessStructural analysis of an anthrol reductase inspires enantioselective synthesis of enantiopure hydroxycycloketones and β-halohydrins
Asymmetric reduction of prochiral ketones, particularly, reductive desymmetrization of 2,2-disubstituted prochiral 1,3-cyclodiketones to produce enantiopure chiral alcohols is challenging. Herein, an anthrol r...
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Article
Pinocembrin Inhibits P2X4 Receptor–Mediated Pyroptosis in Hippocampus to Alleviate the Behaviours of Chronic Pain and Depression Comorbidity in Rats
Neuroinflammation is critical to the comorbidity of chronic pain and depression. Pyroptosis is an inflammatory cell death that is different from apoptosis. Activation of the P2X4 receptor leads to inflammation...
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Article
Open AccessSpatiotemporal trends and ecological determinants of cardiovascular mortality among 2844 counties in mainland China, 2006–2020: a Bayesian modeling study of national mortality registries
Cardiovascular disease (CVD) is the leading cause of death in China. No previous study has reported CVD mortality at county-level, and little was known about the nonmedical ecological factors of CVD mortality ...
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Article
Open AccessImpact of antiretroviral therapy (ART) duration on ART adherence among men who have sex with men (MSM) living with HIV in **an of China
Consistent and complete adherence is considered an essential requirement for patients on antiretroviral therapy (ART). This study aimed to evaluate the impact of ART duration on ART adherence, identify the tre...
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Article
Open AccessComparison of LPS and MS-induced depressive mouse model: behavior, inflammation and biochemical changes
Depression is a mental disease involving complex pathophysiological mechanisms, and there are many ways to establish depressive mouse models. The purpose of this study is to comprehensively compare the behavio...
