![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessROMO1 is required for mitochondrial metabolism during preimplantation embryo development in pigs
Reactive oxygen species (ROS) modulator 1 (ROMO1) is a mitochondrial membrane protein that is essential for the regulation of mitochondrial ROS production and redox sensing. ROMO1 regulates ROS generation with...
-
Article
Open AccessRal GTPase is essential for actin dynamics and Golgi apparatus distribution in mouse oocyte maturation
Ral family is a member of Ras-like GTPase superfamily, which includes RalA and RalB. RalA/B play important roles in many cell biological functions, including cytoskeleton dynamics, cell division, membrane tran...
-
Article
Fipronil induces apoptosis and cell cycle arrest in porcine oocytes during in vitro maturation
Fipronil (FPN) is a widely used phenylpyrazole pesticide that can kill pests by blocking γ-aminobutyric acid (GABA)-gated chloride channels. In addition, there are lack of studies on the effects of FPN on the ...
-
Article
MLL2 is essential for porcine embryo development in vitro
Several germ cell-specific transcription factors essential for ovarian formation and folliculogenesis have been identified and studied. However, their function during early embryo development has been poorly e...
-
Article
Zinc depletion activates porcine metaphase II oocytes independently of the protein kinase C pathway
Zinc is an important trace element that regulates several biological functions. This study investigated the role of zinc in the metaphase (M) II arrest of porcine oocytes. N, N, N’, N’-tetrakis(2-pyridylmethyl...
-
Article
ROCK inhibition prevents early mouse embryo development
ROCK is a Rho-GTPase effector that is important for actin assembly and is involved in various cellular functions, including cell contraction, migration, motility, and tumor cell invasion. In this study, we in...