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Article
Open AccessPhotobody formation spatially segregates two opposing phytochrome B signaling actions of PIF5 degradation and stabilization
Photoactivation of the plant photoreceptor and thermosensor phytochrome B (PHYB) triggers its condensation into subnuclear membraneless organelles named photobodies (PBs). However, the function of PBs in PHYB ...
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Article
Open AccessPathos or logos? How governance legitimacy perception influences individual privacy trade-offs during COVID-19 pandemic
The COVID-19 pandemic has brought attention to the delicate balance between individual privacy concerns and the governance of public health emergencies. Governments are leveraging a wide range of digital metho...
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Article
Open AccessGut microbiota impacts bone via Bacteroides vulgatus-valeric acid-related pathways
Although the gut microbiota has been reported to influence osteoporosis risk, the individual species involved, and underlying mechanisms, remain largely unknown. We performed integrative analyses in a Chinese ...
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Article
Open AccessHalide Perovskite glues activate two-dimensional covalent organic framework crystallites for selective NO2 sensing
Two-dimensional covalent organic frameworks (2D COFs) are promising for gas sensing owing to the large surface area, abundant active sites, and their semiconducting nature. However, 2D COFs are usually produce...
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Article
Open AccessShort term outcomes of extremely low birth weight infants from a multicenter cohort study in Guangdong of China
With the increase in extremely low birth weight (ELBW) infants, their outcome attracted worldwide attention. However, in China, the related studies are rare. The hospitalized records of ELBW infants discharged...
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Article
Open AccessAccurate recognition of colorectal cancer with semi-supervised deep learning on pathological images
Machine-assisted pathological recognition has been focused on supervised learning (SL) that suffers from a significant annotation bottleneck. We propose a semi-supervised learning (SSL) method based on the mea...
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Article
Open AccessRCB initiates Arabidopsis thermomorphogenesis by stabilizing the thermoregulator PIF4 in the daytime
Daytime warm temperature elicits thermomorphogenesis in Arabidopsis by stabilizing the central thermoregulator PHYTOCHROME INTERACTING transcription FACTOR 4 (PIF4), whose degradation is otherwise promoted by the...
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Article
Open AccessReplication of FTO Gene associated with lean mass in a Meta-Analysis of Genome-Wide Association Studies
Sarcopenia is characterized by low skeletal muscle, a complex trait with high heritability. With the dramatically increasing prevalence of obesity, obesity and sarcopenia occur simultaneously, a condition know...
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Article
Open AccessDeep Neck Infection in Systemic Lupus Erythematosus Patients: Real-World Evidence
Systemic lupus erythematosus (SLE) might increase deep neck infection (DNI) risk, but evidence supporting this hypothesis is limited. In this retrospective follow-up study, the SLE–DNI association was investig...
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Article
Open AccessAssociations of autozygosity with a broad range of human phenotypes
In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because...
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Article
Open AccessThe prognostic role of platelet-to-lymphocyte ratio in patients with acute heart failure: A cohort study
Identification of rapid, inexpensive, and reliable prognostic factors can improve survival estimation and guide healthcare in patients with acute heart failure (AHF). In this study, we aimed to determine the p...
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Article
Open AccessNCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches
Phytochromes initiate chloroplast biogenesis by activating genes encoding the photosynthetic apparatus, including photosynthesis-associated plastid-encoded genes (PhAPGs). PhAPGs are transcribed by a bacterial-ty...
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Article
Open AccessComorbidity burden of patients with Parkinson’s disease and Parkinsonism between 2003 and 2012: A multicentre, nationwide, retrospective study in China
Parkinson’s disease (PD) and Parkinsonism are common neurodegenerative disorders with continuously increasing prevalence, causing high global burdens. However, data concerning the comorbidity burden of patient...
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Open AccessGenetic analysis of the TMEM230 gene in Chinese Han patients with Parkinson’s disease
TMEM230 mutations have been recently reported to cause autosomal dominant Parkinson’s disease (PD). However, there are limited studies from different ethnic populations to support the rol...