1,294 Result(s)
within
**an-wen Zhang
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Article
Open AccessEnantiopure trigonal bipyramidal coordination cages templated by in situ self-organized D2h-symmetric anions
The control of a molecule’s geometry, chirality, and physical properties has long been a challenging pursuit. Our study introduces a dependable method for assembling D3-symmetric trigonal bipyramidal coordination...
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Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
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Article
Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
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Open AccessEffects of non-pharmacological interventions for adults with subjective cognitive decline: a network meta-analysis and component network meta-analysis
Non-pharmacological interventions have a myriad of available intervention options and contain multiple components. Whether specific components of non-pharmacological interventions or combinations are superior ...
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The long-term efficacy of eltrombopag in children with immune thrombocytopenia
Immune thrombocytopenia (ITP) is the most common autoimmune disorder characterized by decreased platelet counts and impaired platelet production. Eltrombopag has been demonstrated to be safe and effective for ...
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Open AccessSepM mutation in Streptococcus mutans clinical isolates and related function analysis
Streptococcus mutans (S. mutans) is an important pathogenic bacterium that causes dental caries, while Streptococcus gordonii (S. gordonii) is a non-cariogenic bacterium that inhibits the growth of S. mutans. The...
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Develo** Estimation Equations for the Cerchar Abrasivity Index of Rocks Applicable to TBM Tunnels
Rock abrasivity plays an important role in the machine design, construction scheduling, and budgeting of TBM projects. Establishing several faster and simpler estimation equations for the Cerchar Abrasivity In...
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Open AccessIdentification of lipid-modifying drug targets for autoimmune diseases: insights from drug target mendelian randomization
A growing body of evidence has highlighted the interactions of lipids metabolism and immune regulation. Nevertheless, there is still a lack of evidence regarding the causality between lipids and autoimmune dis...
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Open AccessA multi-kingdom collection of 33,804 reference genomes for the human vaginal microbiome
The human vagina harbours diverse microorganisms—bacteria, viruses and fungi—with profound implications for women’s health. Genome-level analysis of the vaginal microbiome across multiple kingdoms remains limi...
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A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Open AccessPrognostic value of the Naples prognostic score in patients with intrahepatic cholangiocarcinoma after hepatectomy
The Naples Prognostic Score (NPS), integrating inflammatory and nutritional biomarkers, has been reported to be associated with the prognosis of various malignancies, but there is no report on intrahepatic cho...
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Open AccessGlobal Justice Index Report 2023
The Global Justice Index is a multiyear research project based at Fudan Institute for Advanced Study in Social Sciences that assesses the contributions made by each country to achieving greater global justice....
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Article
Single-atom catalysts: controlled synthesis and dynamic mechanism in electrochemical oxygen evolution substitution reactions
Single-atom catalysts (SACs) have attracted much attention in the field of electrocatalysis due to their 100% atomic utilization efficiency, clear active center and adjustable support. The application of SACs ...
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Article
Open AccessASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers
The human methyltransferase and transcriptional coactivator MLL4 and its paralog MLL3 are frequently mutated in cancer. MLL4 and MLL3 monomethylate histone H3K4 and contain a set of uncharacterized PHD fingers...
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Open AccessTheoretical and experimental constraints for the equation of state of dense and hot matter
This review aims at providing an extensive discussion of modern constraints relevant for dense and hot strongly interacting matter. It includes theoretical first-principle results from lattice and perturbative...
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Open AccessIncreased risk of hearing loss associated with MT-RNR1 gene mutations: a real-world investigation among Han Taiwanese Population
Previous studies have implicated inherited mutations in mitochondrial DNA (mtDNA) in sensorineural hearing loss (SNHL). However, the definitive association between mitochondrial 12S rRNA (MT-RNR1) variants and he...
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Comparative analysis of the performance of hepatobiliary agents in depicting MRI features of microvascular infiltration in hepatocellular carcinoma
To compare the ability to depict MRI features of hepatobiliary agents in microvascular infiltration (MVI) of hepatocellular carcinoma (HCC) during different stages of dynamic enhancement MRI.
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Article
Exploration of anomaly separation technology of wide-field electromagnetic method
To improve the accuracy of data processing and interpretation, effective suppression of the regional background field and extraction of the local anomaly field for further analyses represent urgent issues that...
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Article
The Effect of Blending Ratio on the Structure and Properties of the PPR/PS In situ Fiber Reinforced System Prepared by Multi-Flow Vibration Injection Molding
To enhance the mechanical properties of polypropylene random copolymer (PPR), polystyrene (PS) with four different contents were added to the PPR matrix through melt blending. Subsequently, using the Multi-Flo...
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Environmental Enrichment Improves the Recognition Memory in Adult Mice Following Social Isolation via Downregulation of Kv4.2 Potassium Channels
Recognition memory is a cognitive process that enables us to distinguish familiar objects and situations from new items, which is essential for mammalian survival and adaptation to a changing environment. Soci...
