7,482 Result(s)
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**an-Wang Wang
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Article
Vulnerability and Conservation of Nearshore Cetaceans to Increasing Vessel Traffic: The Indo-Pacific Humpback Dolphin in the South China Sea
A comprehensive risk assessment to evaluate the vulnerability of the nearshore cetaceans to increasing marine traffic is lacking. In this study, the risk to Indo-Pacific humpback dolphins (Sousa chinensis) in the...
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Image deep learning in fault diagnosis of mechanical equipment
With the development of industry, more and more crucial mechanical machinery generate wildness demand of effective fault diagnosis to ensure the safe operation. Over the past few decades, researchers have expl...
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GeoVis: a data-driven geographic visualization recommendation system via latent space encoding
As one of the effective means of representing geographic information, geographic visualization can directly improve the cognitive efficiency of users who are perceiving geospatial data. The existing geographic...
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Open AccessAsymmetric total synthesis of polycyclic xanthenes and discovery of a WalK activator active against MRSA
The development of new antibiotics continues to pose challenges, particularly considering the growing threat of multidrug-resistant Staphylococcus aureus. Structurally diverse natural products provide a promising...
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Open AccessHeterogeneous changes in global glacial lakes under coupled climate warming and glacier thinning
Global glacial lakes have expanded markedly in recent decades, accompanied by many catastrophic glacial lake outburst floods. However, our understanding of glacial lake evolution and connections with global wa...
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Pickering emulsion to the construction of spherical nAl/PVDF complexes with excellent thermal properties
Non-uniform mixing of nano-aluminum powder (nAl) with polyvinylidene difluoride (PVDF) affects its thermal properties. Spherical nAl/PVDF complexes were prepared using the Pickering emulsion. Tricosafluorodode...
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Open AccessMulticenter study on clinical outcomes and poor prognostic factors in patients with Klebsiella pneumoniae bacteremia receiving cefoperazone/sulbactam treatment
Infections caused by Klebsiella pneumoniae are common and result in high mortality rates. In vitro studies demonstrated the potency of cefoperazone/sulbactam (CPZ/SUL) against Klebsiella pneumoniae. However, the ...
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Open AccessStrain-tuned incompatible magnetic exchange-interaction in La2NiO4
Magnetic frustration is a route for novel ground states, including spin liquids and spin ices. Such frustration can be introduced through either lattice geometry or incompatible exchange interactions. Here, we...
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Open AccessGlucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer
Cancer cells depend on nicotinamide adenine dinucleotide phosphate (NADPH) to combat oxidative stress and support reductive biosynthesis. One major NADPH production route is the oxidative pentose phosphate pat...
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Article
Open AccessWater body extraction from high spatial resolution remote sensing images based on enhanced U-Net and multi-scale information fusion
Employing deep learning techniques for the semantic segmentation of remote sensing images has emerged as a prevalent approach for acquiring information about water bodies. Yet, current models frequently fall s...
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Open AccessLoss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression
Low response rate, treatment relapse, and resistance remain key challenges for cancer treatment with immune checkpoint blockade (ICB). Here we report that loss of specific tumor suppressors (TS) induces an inf...
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Mass spectrometry-based proteomic landscape of rice reveals a post-transcriptional regulatory role of N6-methyladenosine
Rice is one of the most important staple food and model species in plant biology, yet its quantitative proteomes are largely uncharacterized. Here we quantify the relative protein levels of over 15,000 genes a...
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Open AccessInhibition of DUSP18 impairs cholesterol biosynthesis and promotes anti-tumor immunity in colorectal cancer
Tumor cells reprogram their metabolism to produce specialized metabolites that both fuel their own growth and license tumor immune evasion. However, the relationships between these functions remain poorly unde...
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Resonance behaviour for a bistable system driven by random-phase square-wave signal-modulated noise and multiplicative noise
The stochastic resonance (SR) phenomenon for a bistable system subject to signal-modulated noise and to multiplicative and additive noise is investigated. The signal is modelled as a random-phase asymmetric sq...
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Open AccessWhy are clams steamed with wine in Mediterranean cuisine?
Wine is renowned for its rich content of polyphenols, including resveratrol (Res), known for their health promoting properties. Steamed clam with wine, a popular Mediterranean delicacy that highlights the role...
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Open AccessLong-term operation and dynamic response of dissimilatory nitrate reduction to ammonium process under low-frequency infrared electromagnetic field
Dissimilatory nitrate reduction to ammonium (DNRA) received more attention for its ability to recover ammonium. This study investigated the possibility of low-frequency infrared electromagnetic field (IR-EMF) ...
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Article
Development of an effective QSAR-based hazard threshold prediction model for the ecological risk assessment of aromatic hydrocarbon compounds
The insufficient hazard thresholds of specific individual aromatic hydrocarbon compounds (AHCs) with diverse structures limit their ecological risk assessment. Thus, herein, quantitative structure–activity rel...
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A synthetic TLR4 agonist significantly increases humoral immune responses and the protective ability of an MDCK-cell-derived inactivated H7N9 vaccine in mice
Antigenically divergent H7N9 viruses pose a potential threat to public health, with the poor immunogenicity of candidate H7N9 vaccines demonstrated in clinical trials underscoring the urgent need for more-effe...
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Open AccessSystematic Review and Meta-Analysis of the Diagnostic Accuracy of a Graded Gait and Truncal Instability Rating in Acutely Dizzy and Ataxic Patients
In patients presenting with acute prolonged vertigo and/or gait imbalance, the HINTS [Head-Impulse, Nystagmus, Test-of-Skew] are very valuable. However, their application may be limited by lack of training and...
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Open AccessGlutamate acts on acid-sensing ion channels to worsen ischaemic brain injury
Glutamate is traditionally viewed as the first messenger to activate NMDAR (N-methyl-d-aspartate receptor)-dependent cell death pathways in stroke1,2, but unsuccessful clinical trials with NMDAR antagonists impli...
