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161 Result(s)
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Article
Production of fructo-oligosaccharide syrup through catalysis of Bacillus amyloliquefaciens levanase and immobilized Ba-SacB on cell lysate
Levan is a type of fructan with β-(2, 6) fructosyl linkage. In recent years, levan has been used in the medicinal, food and chemical industries for its excellent physicochemical properties of good thermal stab...
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Article
Permafrost carbon cycle and its dynamics on the Tibetan Plateau
Our knowledge on permafrost carbon (C) cycle is crucial for understanding its feedback to climate warming and develo** nature-based solutions for mitigating climate change. To understand the characteristics ...
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Open AccessMobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma
Lymph node metastasis (LNM) facilitates distant tumor colonization and leads to the high mortality in patients with intrahepatic cholangiocarcinoma (ICC). However, it remains elusive how ICC cells subvert immu...
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Open AccessComplete chloroplast genomes of eight Delphinium taxa (Ranunculaceae) endemic to **njiang, China: insights into genome structure, comparative analysis, and phylogenetic relationships
Delphinium L. represents a taxonomically intricate genus of significant phylogenetic and economic importance in Ranunculaceae. Despite the existence of few chloroplast genome datasets, a comprehensive understandi...
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Open AccessArbuscular mycorrhizal fungi by inducing watermelon roots secretion phthalates, altering soil enzyme activity and bacterial community composition to alleviate the watermelon wilt
Long-term continuous crop** has resulted in the frequent occurrence of fusarium wilt of watermelon (Citrullus lanatus). AMF inoculation can alleviate the continuous crop** barrier and reduce the incidence of ...
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Article
Open AccessAMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
The shift of carbon utilization from primarily glucose to other nutrients is a fundamental metabolic adaptation to cope with decreased blood glucose levels and the consequent decline in glucose oxidation. AMP-...
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Open AccessThe nuclear and mitochondrial genome assemblies of Tetragonisca angustula (Apidae: Meliponini), a tiny yet remarkable pollinator in the Neotropics
The field of bee genomics has considerably advanced in recent years, however, the most diverse group of honey producers on the planet, the stingless bees, are still largely neglected. In fact, only eleven of t...
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Salinity affects C/N ratio through differential responses of carbon and nitrogen metabolism in mangrove Avicennia marina leaves revealed by combined analysis of transcriptome and metabolome
Salt is a critical environmental factor that profoundly impacts plant growth and development. However, the investigation into how plants regulate carbon and nitrogen metabolism in response to different levels ...
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Open AccessTargeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans
Atherosclerosis (AS), a leading cause of cardio-cerebrovascular disease worldwide, is driven by the accumulation of lipid contents and chronic inflammation. Traditional strategies primarily focus on lipid redu...
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Article
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages
Glioblastoma (GBM) is the most aggressive malignant primary brain tumor characterized by a highly heterogeneous and immunosuppressive tumor microenvironment (TME). The symbiotic interactions between glioblasto...
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Article
Effects of Nitrogen Fertilizer Reduction Combined with Foliar Fertilizer Application on the Physiological Characteristics and Yield of High-Quality Japonica Rice
High-quality japonica rice, distinguished by its unique flavor and enriched nutritional value, has attracted significant attention across Asia. The over-application of nitrogen (N) fertilizers, however, is a g...
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Computer-aided rational design strategy based on protein surface charge to improve the thermal stability of a novel esterase from Geobacillus jurassicus
Although Geobacillus are significant thermophilic bacteria source, there are no reports of thermostable esterase gene in Geobacillus jurassicus or rational design strategies to increase the thermal stability of e...
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Article
Alleviating Pentatrichomonas hominis-induced damage in IPEC-J2 cells: the beneficial influence of porcine-derived lactobacilli
Pentatrichomonas hominis is a common intestinal parasitic protozoan that causes abdominal pain and diarrhea, and poses a zoonotic risk. Probiotics, known for enhancing immunity and pathogen resistance, hold promi...
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Open AccessGreengenes2 unifies microbial data in a single reference tree
Studies using 16S rRNA and shotgun metagenomics typically yield different results, usually attributed to PCR amplification biases. We introduce Greengenes2, a reference tree that unifies genomic and 16S rRNA d...
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Open AccessHigh temperature and humidity in the environment disrupt bile acid metabolism, the gut microbiome, and GLP-1 secretion in mice
High temperature and humidity in the environment are known to be associated with discomfort and disease, yet the underlying mechanisms remain unclear. We observed a decrease in plasma glucagon-like peptide-1 l...
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Allelopathy research on the continuous crop** problem of poplar (populus)
The mechanism of decline in continuous plantations is currently a popular research topic in forestry. Continuous crop** is a common obstacle in poplar production and management, and maintaining productivity ...
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Article
Open AccessTargeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity
Current anticancer therapies cannot eliminate all cancer cells, which hijack normal arginine methylation as a means to promote their maintenance via unknown mechanisms. Here we show that targeting protein argi...
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Open AccessLactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model
Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted a relationship between the gut microbiota and gout, whether the microbiota could ameliorate ...
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Comparing the structure and properties of three Eucommia ulmoides wood clones based on the coefficient of variation-rank sum ratio method
Eucommia ulmoides wood is renowned for its high quality, however, there is a lack of research regarding the assessment of its structure and properties. This gap was addressed in the present study by examining thr...
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Article
Open AccessTissue-specific populations from amniotic fluid-derived mesenchymal stem cells manifest variant in vitro and in vivo properties
Amniotic fluid derived mesenchymal stem cells (AFMSCs), shed along the fetal development, exhibit superior multipotency and immunomodulatory properties compared to MSCs derived from other somatic tissues (e.g....