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  1. No Access

    Article

    Production of fructo-oligosaccharide syrup through catalysis of Bacillus amyloliquefaciens levanase and immobilized Ba-SacB on cell lysate

    Levan is a type of fructan with β-(2, 6) fructosyl linkage. In recent years, levan has been used in the medicinal, food and chemical industries for its excellent physicochemical properties of good thermal stab...

    Song Gao, **anghui Qi, Ran Lu, Song Zhu, Guoshi Kan in Biologia (2024)

  2. No Access

    Article

    Permafrost carbon cycle and its dynamics on the Tibetan Plateau

    Our knowledge on permafrost carbon (C) cycle is crucial for understanding its feedback to climate warming and develo** nature-based solutions for mitigating climate change. To understand the characteristics ...

    Leiyi Chen, Guibiao Yang, Yuxuan Bai, **feng Chang in Science China Life Sciences (2024)

  3. Article

    Open Access

    Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma

    Lymph node metastasis (LNM) facilitates distant tumor colonization and leads to the high mortality in patients with intrahepatic cholangiocarcinoma (ICC). However, it remains elusive how ICC cells subvert immu...

    Bao-Ye Sun, Zhu-Tao Wang, Ke-Zhu Chen, Yang Song, **g-Fang Wu in Cell Death Discovery (2024)

  4. Article

    Open Access

    Complete chloroplast genomes of eight Delphinium taxa (Ranunculaceae) endemic to **njiang, China: insights into genome structure, comparative analysis, and phylogenetic relationships

    Delphinium L. represents a taxonomically intricate genus of significant phylogenetic and economic importance in Ranunculaceae. Despite the existence of few chloroplast genome datasets, a comprehensive understandi...

    Chunfeng Song, Junwen Zhu, Huimin Li in BMC Plant Biology (2024)

  5. Article

    Open Access

    Arbuscular mycorrhizal fungi by inducing watermelon roots secretion phthalates, altering soil enzyme activity and bacterial community composition to alleviate the watermelon wilt

    Long-term continuous crop** has resulted in the frequent occurrence of fusarium wilt of watermelon (Citrullus lanatus). AMF inoculation can alleviate the continuous crop** barrier and reduce the incidence of ...

    Wei Li, Chengshang Zhu, Yulu Song, Yufan Yuan, Min Li, Yingkun Sun in BMC Plant Biology (2024)

  6. Article

    Open Access

    AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine

    The shift of carbon utilization from primarily glucose to other nutrients is a fundamental metabolic adaptation to cope with decreased blood glucose levels and the consequent decline in glucose oxidation. AMP-...

    Mengqi Li, Yu Wang, **aoyan Wei, Wei-Feng Cai, Jianfeng Wu, Mingxia Zhu in Cell Research (2024)

  7. Article

    Open Access

    The nuclear and mitochondrial genome assemblies of Tetragonisca angustula (Apidae: Meliponini), a tiny yet remarkable pollinator in the Neotropics

    The field of bee genomics has considerably advanced in recent years, however, the most diverse group of honey producers on the planet, the stingless bees, are still largely neglected. In fact, only eleven of t...

    Rafael Rodrigues Ferrari, Paulo Cseri Ricardo, Felipe Cordeiro Dias in BMC Genomics (2024)

  8. No Access

    Article

    Salinity affects C/N ratio through differential responses of carbon and nitrogen metabolism in mangrove Avicennia marina leaves revealed by combined analysis of transcriptome and metabolome

    Salt is a critical environmental factor that profoundly impacts plant growth and development. However, the investigation into how plants regulate carbon and nitrogen metabolism in response to different levels ...

    **g Li, Ling-Yu Song, Ze-Jun Guo, Chao-Qun Xu, Lu-Dan Zhang in Plant and Soil (2024)

  9. Article

    Open Access

    Targeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans

    Atherosclerosis (AS), a leading cause of cardio-cerebrovascular disease worldwide, is driven by the accumulation of lipid contents and chronic inflammation. Traditional strategies primarily focus on lipid redu...

    Lin Fan, Junwei Liu, Wei Hu, Zexin Chen, Jie Lan, Tongtong Zhang in Cell Research (2024)

  10. No Access

    Article

    IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages

    Glioblastoma (GBM) is the most aggressive malignant primary brain tumor characterized by a highly heterogeneous and immunosuppressive tumor microenvironment (TME). The symbiotic interactions between glioblasto...

    Daqi Li, **efeng Wang, Kexin Chen, Danyang Shan in Cell Death & Differentiation (2024)

  11. No Access

    Article

    Effects of Nitrogen Fertilizer Reduction Combined with Foliar Fertilizer Application on the Physiological Characteristics and Yield of High-Quality Japonica Rice

    High-quality japonica rice, distinguished by its unique flavor and enriched nutritional value, has attracted significant attention across Asia. The over-application of nitrogen (N) fertilizers, however, is a g...

    Yunsheng Song, Minghui Dong, Fei Chen in International Journal of Plant Production (2024)

  12. No Access

    Article

    Computer-aided rational design strategy based on protein surface charge to improve the thermal stability of a novel esterase from Geobacillus jurassicus

    Although Geobacillus are significant thermophilic bacteria source, there are no reports of thermostable esterase gene in Geobacillus jurassicus or rational design strategies to increase the thermal stability of e...

    Runfei Song, ** Zhang, Mengyu Zhu, Lin Lin, Wei Wei, Dongzhi Wei in Biotechnology Letters (2024)

  13. No Access

    Article

    Alleviating Pentatrichomonas hominis-induced damage in IPEC-J2 cells: the beneficial influence of porcine-derived lactobacilli

    Pentatrichomonas hominis is a common intestinal parasitic protozoan that causes abdominal pain and diarrhea, and poses a zoonotic risk. Probiotics, known for enhancing immunity and pathogen resistance, hold promi...

    Yibin Zhu, Haiming Cai, Zhuanqiang Yan, Hanqin Shen in Veterinary Research Communications (2024)

  14. Article

    Open Access

    Greengenes2 unifies microbial data in a single reference tree

    Studies using 16S rRNA and shotgun metagenomics typically yield different results, usually attributed to PCR amplification biases. We introduce Greengenes2, a reference tree that unifies genomic and 16S rRNA d...

    Daniel McDonald, Yueyu Jiang, Metin Balaban, Kalen Cantrell in Nature Biotechnology (2024)

  15. Article

    Open Access

    High temperature and humidity in the environment disrupt bile acid metabolism, the gut microbiome, and GLP-1 secretion in mice

    High temperature and humidity in the environment are known to be associated with discomfort and disease, yet the underlying mechanisms remain unclear. We observed a decrease in plasma glucagon-like peptide-1 l...

    Song Chen, Zongren Hu, Jianbang Tang, Haipeng Zhu, Yuhua Zheng in Communications Biology (2024)

  16. No Access

    Article

    Allelopathy research on the continuous crop** problem of poplar (populus)

    The mechanism of decline in continuous plantations is currently a popular research topic in forestry. Continuous crop** is a common obstacle in poplar production and management, and maintaining productivity ...

    Tao Song, Jia-Xu Chen, Lin-Miao Shan, Yu-Chen Qian, Mo-**an Chen in Phytochemistry Reviews (2024)

  17. Article

    Open Access

    Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity

    Current anticancer therapies cannot eliminate all cancer cells, which hijack normal arginine methylation as a means to promote their maintenance via unknown mechanisms. Here we show that targeting protein argi...

    Haojie Dong, **n He, Lei Zhang, Wei Chen, Yi-Chun Lin, Song-Bai Liu in Nature Cancer (2024)

  18. Article

    Open Access

    Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model

    Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted a relationship between the gut microbiota and gout, whether the microbiota could ameliorate ...

    Yang Fu, Yong-Song Chen, Dai-Yang **a, **ao-Dan Luo in npj Biofilms and Microbiomes (2024)

  19. No Access

    Article

    Comparing the structure and properties of three Eucommia ulmoides wood clones based on the coefficient of variation-rank sum ratio method

    Eucommia ulmoides wood is renowned for its high quality, however, there is a lack of research regarding the assessment of its structure and properties. This gap was addressed in the present study by examining thr...

    Shuan Ren, Borui Zhu, Shuang Zhao, Ke Song, Jie Guo in Wood Science and Technology (2024)

  20. Article

    Open Access

    Tissue-specific populations from amniotic fluid-derived mesenchymal stem cells manifest variant in vitro and in vivo properties

    Amniotic fluid derived mesenchymal stem cells (AFMSCs), shed along the fetal development, exhibit superior multipotency and immunomodulatory properties compared to MSCs derived from other somatic tissues (e.g....

    Nengqing Liu, Yi Cheng, Ding Wang, Hongmei Guan, Diyu Chen, Juan Zeng in Human Cell (2024)

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