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SLFN11 promotes clear cell renal cell carcinoma progression via the PI3K/AKT signaling pathway

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  1. Article

    Open Access

    Systematic investigation of the material basis, effectiveness and safety of Thesium chinense Turcz. and its preparation Bairui Granules against lung inflammation

    Thesium chinense Turcz. (Named as Bai Rui Cao in Chinese) and its preparations (e.g., Bairui Granules) have been used to treat inflammatory diseases, such as acute mastitis, lobar pneumonia, tonsillitis, coronavi...

    Guang-Cheng Peng, **-Hua Hao, Yue-Qin Guan, Ying-Yue Wang in Chinese Medicine (2024)

  2. Article

    Open Access

    Specific convulsions and brain damage in children hospitalized for Omicron BA.5 infection: an observational study using two cohorts

    SARS-CoV-2 continues to mutate over time, and reports on children infected with Omicron BA.5 are limited. We aimed to analyze the specific symptoms of Omicron-infected children and to improve patient care.

    Yuan-Yuan Pei, Hong-Li Wang, Gen-Quan Yin, Yi Xu in World Journal of Pediatrics (2024)

  3. Article

    Open Access

    Association of fish and meat consumption with non-alcoholic fatty liver disease: Guangzhou Biobank Cohort Study

    Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. Unhealthy dietary habit is one of major risk factors of NAFLD. However, the associations between specific types of fish and m...

    Rui Zhen Wang, Wei Sen Zhang, Chao Qiang Jiang, Feng Zhu, Ya Li ** in BMC Public Health (2023)

  4. Article

    Open Access

    Prevalence and factors associated with flares following COVID-19 mRNA vaccination in patients with rheumatoid arthritis, psoriatic arthritis and spondyloarthritis: a national cohort study

    To determine prevalence and factors associated with flares post Coronavirus disease 2019 (COVID-19) mRNA vaccination in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and spondyloarthritis ...

    Warren Fong, Ting Hui Woon, Li-Ching Chew, Andrea Low in Advances in Rheumatology (2023)

  5. Article

    Open Access

    Predictive role of pre-thrombolytic hs-CRP on the safety and efficacy of intravenous thrombolysis in acute ischemic stroke

    To investigate the predictive role of pre-thrombolytic high sensitivity C-reactive protein (hs-CRP) on the safety and efficacy of intravenous thrombolysis in patients with acute ischemic stroke (AIS).

    Xu-Dong Cheng, Duo-Zi Wang, Qi Zhang, Jian-Hong Wang, Bing-Hu Li in BMC Neurology (2023)

  6. Article

    Open Access

    Establishment and validation of an AI-aid method in the diagnosis of myocardial perfusion imaging

    This study aimed to develop and validate an AI (artificial intelligence)-aid method in myocardial perfusion imaging (MPI) to differentiate ischemia in coronary artery disease.

    Ruyi Zhang, Peng Wang, Yanzhu Bian, Yan Fan, Jianming Li, Xuehui Liu in BMC Medical Imaging (2023)

  7. Article

    Open Access

    Pseudomonas aeruginosa isolation is an important predictor for recurrent hemoptysis after bronchial artery embolization in patients with idiopathic bronchiectasis: a multicenter cohort study

    Nearly half of bronchiectasis patients receiving bronchial artery embolization (BAE) still have recurrent hemoptysis, which may be life-threatening. Worse still, the underlying risk factors of recurrence remai...

    Le-Le Wang, Hai-Wen Lu, Ling-Ling Li, Yong-Hua Gao, Yu-Hua Xu in Respiratory Research (2023)

  8. Article

    Open Access

    Safety and immunogenicity of a mosaic vaccine booster against Omicron and other SARS-CoV-2 variants: a randomized phase 2 trial

    An ongoing randomized, double-blind, controlled phase 2 trial was conducted to evaluate the safety and immunogenicity of a mosaic-type recombinant vaccine candidate, named NVSI-06-09, as a booster dose in subj...

    Nawal Al Kaabi, Yun Kai Yang, Yu Liang, Ke Xu in Signal Transduction and Targeted Therapy (2023)

  9. Article

    Open Access

    Association of alcohol use with memory decline in middle-aged and older Chinese: a longitudinal cohort study

    Previous studies on associations of alcohol use with memory decline showed inconclusive results. We examined these associations using longitudinal data from the Guangzhou Biobank Cohort Study (GBCS) and explor...

    Yu Meng Tian, Wei Sen Zhang, Chao Qiang Jiang, Feng Zhu, Ya Li ** in BMC Psychiatry (2022)

  10. Article

    Open Access

    Application of machine learning model to predict osteoporosis based on abdominal computed tomography images of the psoas muscle: a retrospective study

    With rapid economic development, the world's average life expectancy is increasing, leading to the increasing prevalence of osteoporosis worldwide. However, due to the complexity and high cost of dual-energy x...

    Cheng-bin Huang, Jia-sen Hu, Kai Tan, Wei Zhang, Tian-hao Xu, Lei Yang in BMC Geriatrics (2022)

  11. Article

    Open Access

    Correlation of CT-derived pectoralis muscle status and COVID-19 induced lung injury in elderly patients

    To explore the association between CT-derived pectoralis muscle index (PMI) and COVID-19 induced lung injury.

    Pei Ying-hao, Zhang Hai-dong, Fang Yuan, Liu Yong-kang, Liang Sen in BMC Medical Imaging (2022)

  12. Article

    Open Access

    Hearing loss and depressive symptoms in older Chinese: whether social isolation plays a role

    Existing evidence links hearing loss to depressive symptoms, with the extent of association and underlying mechanisms remaining inconclusive. We conducted a cross-sectional study to examine the association of ...

    Hao Huang, Jiao Wang, Chao Qiang Jiang, Feng Zhu, Ya Li **, Tong Zhu in BMC Geriatrics (2022)

  13. Article

    Open Access

    Psychiatric symptoms are not associated with circulating CRP concentrations after controlling for medical, social, and demographic factors

    Elevated serum concentrations (>3 mg/L) of the acute-phase protein, C-reactive protein (CRP), is used as a clinical marker of inflammation and is reported to be a strong risk factor for cardiovascular disease....

    Leandra K. Figueroa-Hall, Bohan Xu, Rayus Kuplicki in Translational Psychiatry (2022)

  14. Article

    Open Access

    Association between spicy foods consumption and cardiovascular disease risk factors: Guangzhou Biobank Cohort Study

    Evidence regarding the association of spicy foods intake with cardiovascular disease (CVD) risk factors was less clear, especially in those with diabetes. We hereby examined the association of spicy foods inta...

    Yu Zhang, Zi Long Lu, Wei Sen Zhang, Ya Li **, Tong Zhu, Lin Xu in BMC Public Health (2022)

  15. Article

    Open Access

    Associations of face-to-face and non-face-to-face social isolation with all-cause and cause-specific mortality: 13-year follow-up of the Guangzhou Biobank Cohort study

    Although social isolation has been associated with a higher mortality risk, little is known about the potential different impacts of face-to-face and non-face-to-face isolation on mortality. We examined the pr...

    Jiao Wang, Wei Sen Zhang, Chao Qiang Jiang, Feng Zhu, Ya Li ** in BMC Medicine (2022)

  16. Article

    Open Access

    Management of pulmonary arteriovenous malformations involves additional factors aside from the diameter of feeding arteries: a 3-year case-case retrospective analysis

    Pulmonary arteriovenous malformations (PAVMs) are rare but cause various manifestations. Although the diameter of feeding arteries has been linked to treatment decisions, relationships among the characteristic...

    Xu Ma, Ling-Ling Li, Dong Yu, Bing Jie, Sen Jiang in Respiratory Research (2022)

  17. Article

    Open Access

    Correlation between the accumulation of skin glycosylation end products and the development of type 2 diabetic peripheral neuropathy

    The accumulation of advanced glycation end products (AGEs) occurring in skin tissues can be measured by AGE Reader. Here, we assessed the correlation between AGEs values and the development of type 2 diabetic ...

    **ng-Wang Zhao, Wan-Xu Yue, Sen-Wei Zhang, Qiu Chen in BMC Endocrine Disorders (2022)

  18. Article

    Open Access

    Obesity indicators as mediators of association between daytime nap** and type 2 diabetes mellitus: the Guangzhou Biobank Cohort Study

    To examine the mediating effect of obesity indicators on the association between daytime nap** and type 2 diabetes mellitus (T2DM) qualitatively and quantitatively using baseline data from the Guangzhou Biob...

    **g Yi **ao, Wei Sen Zhang, Chao Qiang Jiang, Ya Li **, Feng Zhu in BMC Public Health (2022)

  19. Article

    Open Access

    Higher total white blood cell and neutrophil counts are associated with an increased risk of fatal stroke occurrence: the Guangzhou biobank cohort study

    Chronic inflammatory diseases are linked to an increased risk of stroke events. The white blood cell (WBC) count is a common marker of the inflammatory response. However, it is unclear whether the WBC count, i...

    Zhi-bing Hu, Ze-xiong Lu, Feng Zhu, Cao-qiang Jiang, Wei-sen Zhang in BMC Neurology (2021)

  20. Article

    Open Access

    An assessment of morphological and pathological changes in paravertebral muscle degeneration using imaging and histological analysis: a cross-sectional study

    The high signal of paravertebral muscle (PVM) on T2-weighted image (T2WI) is usually considered to be fatty degeneration. However, it is difficult to distinguish inflammatory edema from fatty degeneration on T...

    Ding-Chao Zhu, Jia-Hao Lin, Jia-**g Xu, Qiang Guo in BMC Musculoskeletal Disorders (2021)

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