12,590 Result(s)
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**-ming Li
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Article
Initial orbit determination of some cislunar orbits based on short-arc optical observations
Ground- and space-based optical observation is an efficient way to catalog objects in the cislunar space. Initial orbit determination based on optical data is still an open problem for cislunar objects. The mo...
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XOR spin logic operated by unipolar current based on field-free spin–orbit torque switching induced by a lateral interface
Spin logics have emerged as a promising avenue for the development of logic-in-memory architectures. In particular, the realization of XOR spin logic gates using a single spin–orbit torque device shows great p...
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A Mixed Reality-Based Chemistry Experiment Learning System to Facilitate Chemical Laboratory Safety Education
It is difficult for students to learn the concepts of chemical laboratory safety education from actual experiences because the traditional teaching model prohibits students from performing dangerous operations...
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Raddeanin A Protects the BRB Through Inhibiting Inflammation and Apoptosis in the Retina of Alzheimer’s Disease
Neuroinflammation and endothelial cell apoptosis are prominent features of blood–brain barrier (BBB) disruption, which have been described in Alzheimer’s disease (AD) and can predict cognitive decline. Recent ...
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An innovative integrated approach to automatic defect detection system of cell phone case manufacturing in an empirical implementation
In this study an innovative integrated approach is proposed to develop a design schema for automatic defect detection system. This system has been successfully implemented in an empirical factory setting. In a...
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Activation AMPK in Hypothalamic Paraventricular Nucleus Improves Renovascular Hypertension Through ERK1/2-NF-κB Pathway
Hypertension is a globally prevalent disease, but the pathogenesis remains largely unclear. AMP-activated protein kinase (AMPK) is a nutrition-sensitive signal of cellular energy metabolism, which has a certai...
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Open AccessAdenine base editing-mediated exon skip** restores dystrophin in humanized Duchenne mouse model
Duchenne muscular dystrophy (DMD) affecting 1 in 3500–5000 live male newborns is the frequently fatal genetic disease resulted from various mutations in DMD gene encoding dystrophin protein. About 70% of DMD-caus...
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Electricity generated by upstream proton diffusion in two-dimensional nanochannels
The movement of ions along the pressure-driven water flow in narrow channels, known as downstream ionic transport, has been observed since 1859 to induce a streaming potential and has enabled the creation of v...
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Open AccessDihydroorotase MoPyr4 is required for development, pathogenicity, and autophagy in rice blast fungus
Dihydroorotase (DHOase) is the third enzyme in the six enzymatic reaction steps of the endogenous pyrimidine nucleotide de novo biosynthesis pathway, which is a metabolic pathway conserved in both bacteria and...
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Accelerated learning and co-optimization of elastocaloric effect and stress hysteresis of elastocaloric alloys
The development of high-performance advanced elastocaloric alloys is crucial for the implementation of elastocaloric refrigeration. Here, we present a machine learning (ML) framework to accelerate the developm...
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Elimination of cracks in stainless steel casings via 3D printed sand molds with an internal topology structure
The important supporting component in a gas turbine is the casing, which has the characteristics of large size, complex structure, and thin wall. In the context of existing 3DP sand casting processes, casting ...
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Technological solutions to foster preschool children’s spatial ability: A situational interactive e-book approach
Spatial ability is a significant component of mathematical ability and a foundation for children to master mathematical knowledge. Although many studies have confirmed that technology can enhance children’s le...
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Open AccessAsymmetric total synthesis of polycyclic xanthenes and discovery of a WalK activator active against MRSA
The development of new antibiotics continues to pose challenges, particularly considering the growing threat of multidrug-resistant Staphylococcus aureus. Structurally diverse natural products provide a promising...
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Retroperitoneal leakage as an important cause of acquired ultrafiltration decline in peritoneal dialysis: clinical characteristics and related risk factors
Peritoneal dialysis (PD) is a widely-used renal replacement therapy while low ultrafiltration volume usually results in technique failure. Retroperitoneal leakage has been reported to be one of the causes of a...
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Open AccessHarnessing virus flexibility to selectively capture and profile rare circulating target cells for precise cancer subty**
The effective isolation of rare target cells, such as circulating tumor cells, from whole blood is still challenging due to the lack of a capturing surface with strong target-binding affinity and non-target-ce...
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Highly stable strain sensor using rGO decorated with multi-component alloy nanoparticles for human motion monitoring
Wearable, flexible devices have garnered widespread attention in the realm of human motion and life activity detection. Currently, the development of simple, green, and easily scalable methods for fabricating ...
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Open AccessKey propagation pathways of extreme precipitation events revealed by climate networks
The comprehensive understanding of propagation patterns of extreme precipitation events (EPEs) is essential for early warning of associated hazards such as floods and landslides. In this study, we utilize clim...
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Open AccessIncreased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway
Helicobacter pylori (HP) infection initiates and promotes gastric carcinogenesis. ONECUT2 shows promise for tumor diagnosis, prognosis, and treatment. This study explored ONECUT2’s role and the specific mechanism...
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Rab11b promotes M1-like macrophage polarization by restraining autophagic degradation of NLRP3 in alcohol-associated liver disease
Macrophage polarization is vital to mounting a host defense or repairing tissue in various liver diseases. Excessive activation of the NLR family pyrin domain containing 3 (NLRP3) inflammasome is related to th...
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Open AccessEpidemiological trends of subarachnoid hemorrhage at global, regional, and national level: a trend analysis study from 1990 to 2021
Subarachnoid hemorrhage (SAH) is a subtype of hemorrhagic stroke characterized by high mortality and low rates of full recovery. This study aimed to investigate the epidemiological characteristics of SAH betwe...
