-
Article
Open AccessProspective validation of the role of PET/CT in detecting disease after neoadjuvant chemotherapy in advanced ovarian cancer
The study aimed to compare the diagnostic accuracies of 2-[18F]FDG PET/CT and contrast-enhanced CT (ceCT) after neoadjuvant chemotherapy (NACT) in advanced ovarian cancer (OC).
-
Article
Open AccessWRN loss accelerates abnormal adipocyte metabolism in Werner syndrome
Metabolic dysfunction is one of the main symptoms of Werner syndrome (WS); however, the underlying mechanisms remain unclear. Here, we report that loss of WRN accelerates adipogenesis at an early stage both in vi...
-
Chapter and Conference Paper
Malaysian Local Fruits E-Marketplace System with Intelligent Promotional Feature
Malaysia is a home to many types of tropical fruit trees due to the tropical climate with high humidity. Fruit trees are planted on a commercial scale and on a small-scale. However, the current procurement sys...
-
Article
Rational design of platinum(II) complexes with orthogonally oriented triazolyl ligand with emission enhancement characteristics for cancer chemotherapy in vivo
The mitochondria are essential for tumorigenesis and have been regarded as important targets in cancer chemotherapy. Herein, the mitochondria-targeted platinum(II) complexes have been prepared. The introductio...
-
Chapter and Conference Paper
Attendance Management System with Half-Covered and Full-Facial Recognition Feature
Manual way of tracking attendance is inefficient and has vulnerability in protecting personal data. Various attendance management systems have been introduced to replace the manual attendance tracking process....
-
Living Reference Work Entry In depth
Healthy Aging and Well-Being of Older Adults in Hong Kong
Aging population has been a worldwide issue, and governments around the world are promoting healthy aging and well-being of older adults. In order to improve the quality of life of older populations, different...
-
Chapter and Conference Paper
Introducing Coding to Children with Scratch: A Pilot Study
As digital literacy is necessary in the modern workplace, programming or coding skills have been deemed as an important competence in 21st century education. However, learning to code or program is generally p...
-
Chapter and Conference Paper
Mobile Application for After School Pickup Solution: Malaysia Perspectives
School pickup is a daily routine for most parents during the school term. The use of private vehicles as daily commute to transport students to and from schools has caused school-related traffic congestion and...
-
Chapter and Conference Paper
School Canteen Food Ordering Application with Food Allergy Alert Feature: Malaysia Perspective
School canteen is one of the indispensable educational resources and plays an important role in one’s school life. As the school canteen supplies on average of a third of a student’s daily food consumption, it...
-
Chapter and Conference Paper
Mobile Application for Bidding Durians
Normally, there are intermediaries between durian farmers and the end consumers. As a result, the retail durian price in the market is generally twice the farm price. As durians are perishable and taste best w...
-
Chapter and Conference Paper
A Pilot Study of Learning Programming with ScratchJr
Embedding technological tools in learning and providing learning environment that can support wider use of technology to equip students with computational thinking have become the trend in education. Computati...
-
Article
Open AccessClonal relationship and alcohol consumption-associated mutational signature in synchronous hypopharyngeal tumours and oesophageal squamous cell carcinoma
The patients with dual oesophageal squamous cell carcinoma (ESCC) and hypopharyngeal cancer (HPC) have poor prognosis; their underlying genetic pathogenesis is unclear. We hypothesise that development of synch...
-
Article
Open AccessWRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome
Werner Syndrome (WS) is an autosomal recessive disorder characterized by premature aging due to mutations of the WRN gene. A classical sign in WS patients is short stature, but the underlying mechanisms are not w...
-
Article
Mortality outcomes and survival patterns of patients with myeloproliferative neoplasms in Malaysia
Prognostication of myeloproliferative neoplasm (MPN) has always been challenging, even with the advent of Janus kinase 2 (JAK2 V617F) molecular studies. The survival pattern of patients diagnosed with MPN in d...
-
Chapter and Conference Paper
The Development of Artisanal Food Products E-marketplace with Intelligent Depletion Feature
As the technology today is moving forward at an exponential rate, e-commerce platforms have become a common trend for business. The platforms allow the implementation of Consumer-to-Consumer (C2C) business mod...
-
Chapter
The Role of Tibial Force Sensors in Total Knee Arthroplasty
Increasing demand for total knee arthroplasty (TKA) and the costs associated with revision surgery drive investigations aimed at determining etiologies for aseptic failure. Additionally, clinically significant...
-
Chapter
Palliative Care in Selected Economies in Asia: Taiwan, Singapore and Hong Kong
People are living longer nowadays. Medical advancement has helped to prolong lives and a lot of diseases are curable. However, patients with life-limiting and terminal illnesses still suffer. Palliative care i...
-
Article
Prognostic impact of the adverse molecular-genetic profile on long-term outcomes following allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia
The impact of adverse risk genetic profiles on outcomes in acute myeloid leukemia (AML) patients following allogeneic hematopoietic stem cell transplantation (HCT) has not been fully elucidated. Accordingly, w...
-
Article
Naloxone Facilitates Contextual Learning and Memory in a Receptor-Independent and Tet1-Dependent Manner
Opioids, like morphine and naloxone, regulate the proliferation and neuronal differentiation of neural stem cells (NSCs) in a receptor-independent and ten-eleven translocation methylcytosine dioxygenase (TET1)...
-
Article
Oxycodone in the Opioid Epidemic: High ‘Liking’, ‘Wanting’, and Abuse Liability
It is estimated that nearly a third of people who abuse drugs started with prescription opioid medicines. Approximately, 11.5 million Americans used prescription drugs recreationally in 2016, and in 2018, 46,8...
