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Article
Open AccessAn oxylipin signal confers protection against antifungal echinocandins in pathogenic aspergilli
Aspergillus fumigatus is the leading causative agent of life-threatening invasive aspergillosis in immunocompromised individuals. One antifungal class used to treat Aspergillus infections is the fungistatic echin...
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Article
Open AccessCopper starvation induces antimicrobial isocyanide integrated into two distinct biosynthetic pathways in fungi
The genomes of many filamentous fungi, such as Aspergillus spp., include diverse biosynthetic gene clusters of unknown function. We previously showed that low copper levels upregulate a gene cluster that includes...
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Article
Open AccessFungal oxylipins direct programmed developmental switches in filamentous fungi
Filamentous fungi differentiate along complex developmental programs directed by abiotic and biotic signals. Currently, intrinsic signals that govern fungal development remain largely unknown. Here we show tha...
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Article
Open AccessLipo-chitooligosaccharides as regulatory signals of fungal growth and development
Lipo-chitooligosaccharides (LCOs) are signaling molecules produced by rhizobial bacteria that trigger the nodulation process in legumes, and by some fungi that also establish symbiotic relationships with plant...