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  1. Article

    Open Access

    An oxylipin signal confers protection against antifungal echinocandins in pathogenic aspergilli

    Aspergillus fumigatus is the leading causative agent of life-threatening invasive aspergillosis in immunocompromised individuals. One antifungal class used to treat Aspergillus infections is the fungistatic echin...

    Dante G. Calise, Sung Chul Park, ** Woo Bok, Gustavo H. Goldman in Nature Communications (2024)

  2. Article

    Open Access

    Copper starvation induces antimicrobial isocyanide integrated into two distinct biosynthetic pathways in fungi

    The genomes of many filamentous fungi, such as Aspergillus spp., include diverse biosynthetic gene clusters of unknown function. We previously showed that low copper levels upregulate a gene cluster that includes...

    Tae Hyung Won, ** Woo Bok, Nischala Nadig, Nandhitha Venkatesh in Nature Communications (2022)

  3. Article

    Open Access

    Fungal oxylipins direct programmed developmental switches in filamentous fungi

    Filamentous fungi differentiate along complex developmental programs directed by abiotic and biotic signals. Currently, intrinsic signals that govern fungal development remain largely unknown. Here we show tha...

    Mengyao Niu, Breanne N. Steffan, Gregory J. Fischer in Nature Communications (2020)

  4. Article

    Open Access

    Lipo-chitooligosaccharides as regulatory signals of fungal growth and development

    Lipo-chitooligosaccharides (LCOs) are signaling molecules produced by rhizobial bacteria that trigger the nodulation process in legumes, and by some fungi that also establish symbiotic relationships with plant...

    Tomás Allen Rush, Virginie Puech-Pagès, Adeline Bascaules in Nature Communications (2020)