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1,534 Result(s)
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Article
Open AccessSurvival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study
Most gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has significantly improved the survival of patients with GISTs. We aimed to evalu...
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Open AccessDissecting the vascular-cognitive nexus: energetic vs. conventional hemodynamic parameters
Blood pressure or flow measurements have been associated with vascular health and cognitive function. We proposed that energetic hemodynamic parameters may provide a more nuanced understanding and stronger cor...
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Open AccessA holistic lifestyle mobile health intervention for the prevention of type 2 diabetes and common mental disorders in Asian women with a history of gestational diabetes: a randomised control trial with 3-year follow-up protocol
Women with a history of gestational diabetes mellitus (GDM) are 12-fold more likely to develop type 2 diabetes (T2D) 4–6 years after delivery than women without GDM. Similarly, GDM is associated with the devel...
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Open AccessThe role of cytoreductive nephrectomy in metastatic renal cell carcinoma in immune-oncology era (SEVURO-CN): study protocol for a multi-center, prospective, randomized trial
The role of cytoreductive nephrectomy (CN) in the treatment of metastatic renal cell carcinoma (mRCC) remains unclear in the immuno-oncology (IO) era. The results of two randomized trials, CARMENA and SURTIME,...
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Open AccessDecision regret after prostate biopsy for prostate cancer diagnosis: a Korean multicenter cohort study
Many people struggle with the choice in a series of processes, from prostate cancer (PCa) diagnosis to treatment. We investigated the degree of regret after the prostate biopsy (PBx) and relevant factors in pa...
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Open AccessCharacterising Parent-Appeal Marketing on Foods for Children: A Sco** Review
This sco** review examines current evidence on parent-appeal marketing on the front-of-pack of food products for children and the impacts on parents’ perceptions, intentions, and behaviours.
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Reevaluating the link between Down Syndrome and uveitis
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Open AccessHigh prevalence of exon-13 variants in USH2A-related retinal dystrophies in Taiwanese population
Biallelic pathogenic variants in USH2A lead to Usher syndrome or non-syndromic retinitis pigmentosa, and shown to have geographical and ethnical distribution in previous studies. This study provided a deeper unde...
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Open AccessDigital twin mathematical models suggest individualized hemorrhagic shock resuscitation strategies
Optimizing resuscitation to reduce inflammation and organ dysfunction following human trauma-associated hemorrhagic shock is a major clinical hurdle. This is limited by the short duration of pre-clinical studi...
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Open AccessEditorial expression of concern: Protective effect of Curcuma longa L. extract on CCl4-induced acute hepatic stress
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Open AccessAssociations between obesity, a composite risk score for probable long COVID, and sleep problems in SARS-CoV-2 vaccinated individuals
Preliminary data suggests that obesity might hasten the decline in mRNA vaccine-induced immunity against SARS-CoV-2. However, whether this renders individuals with obesity more susceptible to long COVID sympto...
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Insights into the roles of Apolipoprotein E in adipocyte biology and obesity
Apolipoprotein E (APOE) is a multifunctional protein expressed by various cell types, including hepatocytes, adipocytes, immune cells of the myeloid lineage, vascular smooth muscle cells, astrocytes, etc. Init...
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Open AccessCorrection to: Epidemiology of Osteoporosis in Patients with Chronic Obstructive Pulmonary Disease in Taiwan
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Open AccessPopulation-Based Prognostic Models for Head and Neck Cancers Using National Cancer Registry Data from Taiwan
This study aims to raise awareness of the disparities in survival predictions among races in head and neck cancer (HNC) patients by develo** and validating population-based prognostic models specifically tai...
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The role of endogenous opioids in mindfulness and sham mindfulness-meditation for the direct alleviation of evoked chronic low back pain: a randomized clinical trial
Chronic low back pain (cLBP) is the most prevalent chronic pain condition. There are no treatments that haven been found to directly assuage evoked cLBP. To this extent, mindfulness-meditation is a promising p...
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Open AccessValidation of the Korean version of the Summated Xerostomia Inventory among older adults residing in nursing homes
Xerostomia is commonly experienced by older individuals. We sought to develop and evaluate the reliability and validity of the Korean version of the Summated Xerostomia Inventory (K-SXI) among older adults res...
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Marfan’s syndrome is associated with a greater risk of Peyronie’s disease: a case-control study of the TriNetX database
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Open AccessUnique clinical and electrophysiological features in the peripheral nerve system in patients with sialidosis – a case series study
To investigate the peripheral nervous system involvement in S sialidosis with typical features of myoclonus, seizure, and giant waves in somatosensory evoked potentials suggesting hyperexcitability in the central...
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Carpal tunnel syndrome
Carpal tunnel syndrome (CTS) is the most common nerve entrapment disorder worldwide. The epidemiology and risk factors, including family burden, for develo** CTS are multi-factorial. Despite much research, i...
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Open AccessPrediction of adolescent weight status by machine learning: a population-based study
Adolescent weight problems have become a growing public health concern, making early prediction of non-normal weight status crucial for effective prevention. However, few temporal prediction tools for adolesce...