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  1. No Access

    Protocol

    Lateral Filter Array Microfluidic Devices for Detecting Circulating Tumor Cells

    Circulating tumor cells (CTCs) are an important liquid biopsy biomarker for next-generation cancer diagnosis and prognosis. However, their clinical usage is hindered by the rarity of CTCs in patient’s peripher...

    Kangfu Chen, Thomas J. George, Z. Hugh Fan in Microfluidic Systems for Cancer Diagnosis (2023)

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    Protocol

    Single-Cell Micropatterning by Non-fouling Hydrogels

    Micropatterned substrate is a unique method for studying cell biology at the single-cell level. Using photolithography to create binary patterns of cell-adherent peptide surrounding by non-fouling cell-repelle...

    Wengang Liu, Ting-Hsuan Chen, Jiandong Ding in Single-Cell Assays (2023)

  3. No Access

    Protocol

    High-Throughput Separation and Enrichment of Rare Malignant Tumor Cells from Large-Volume Effusions by Inertial Microfluidics

    Detection of malignant tumor cells (MTCs) in pleural effusions is essential for determining the malignancy. However, the sensitivity of MTC detection is significantly decreased due to the existence of a massiv...

    Chen Ni, Zhixian Zhu, Zheng Zhou, Nan **ang in Microfluidic Systems for Cancer Diagnosis (2023)

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    Protocol

    Microfluidics-Enabled Isolation and Single-Cell Analysis of Circulating Tumor Cells

    Microfluidic platforms enable the enrichment and analysis of circulating tumor cells (CTCs), a potential biomarker for cancer diagnosis, prognosis, and theragnosis. Combined with immunocytochemistry/immunofluo...

    Minh-Chau N. Le, Kierstin A. Smith, Morteza Alipanah, Kangfu Chen… in Single-Cell Assays (2023)

  5. No Access

    Protocol

    CdS Quantum Dots Modified Photoelectrochemical Biosensor for TATA-Binding Protein Probing

    The photoelectrochemical (PEC) biosensor, in which light is utilized to excite the photoactive species and current is employed as the detection signal, is a newly appeared yet dynamically develo** technique ...

    Yi-Fan Ruan, **ao-Mei Shi, Hai-Yan Wang, Wei-Wei Zhao, **g-Juan Xu… in Quantum Dots (2020)

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    Protocol

    Detection of Tetanus Antibody Applying a Cu-Zn-In-S/ZnS Quantum Dot-Based Lateral Flow Immunoassay

    Lateral flow test strip (LFTS) enables rapid, portable, and low-cost point-of-care testing (POCT) diagnosis. Quantum dots (QDs), which are fluorescent semiconductor nanocrystals with distinctive and unique pho...

    Hong-Min Meng, Juan Chen, Lingbo Qu, Zhaohui Li in Quantum Dots (2020)

  7. No Access

    Protocol

    MicroPET, MicroSPECT, and NIR Fluorescence Imaging of Biomolecules In Vivo

    Molecular imaging is a newly merged multidisciplinary subject that requires contributions from biology, medical physics, and chemistry/radiochemistry. Integrin αvβ3, a cell adhesion molecule, plays pivotal roles ...

    Zi-Bo Li, **aoyuan Chen in Micro and Nano Technologies in Bioanalysis (2009)