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    GPCR Allosteric Modulator Discovery

    G protein-coupled receptors (GPCRs) influence virtually every aspect of human physiology; about one-third of all marketed drugs target members of this family. GPCR allosteric ligands hold the promise of improv...

    Yiran Wu, Jiahui Tong, Kang Ding, Qingtong Zhou… in Protein Allostery in Drug Discovery (2019)