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Chapter and Conference Paper
Einfluss des vaskulären Permeabilitätsfaktor VEGF auf die Tumorzelldissemination bei Patienten mit Ösophaguskarzinom
VEGF does not only induce neo-angiogenesis of malignant tumors but also increases vascular permeability and might facilitate tumor cell dissemination. The expression of VEGF, microvessel count and the incidenc...
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Chapter
Sertoli Cell-Specific Gene Expression in Conditionally Immortalized Cell Lines
A set of conditionally immortalized Sertoli cell lines has recently been established in this laboratory from H-2K h -tsA58 transgenic mice (Walther et al., 1996)...
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Chapter
Angioarchitecture of the Human Spermatic Cord
In the spermatic cord of all species investigated a tightly organized venous network around the testicular artery has been described, with certain species-specific differences (Hess et al., 1984; Noordhuizen-S...
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Chapter
Endothelin-1 and Its Receptors in the Human Epididymis
Endothelin-1 (ET-1) is a potent vasoconstrictor localized for the first time in porcine aortic endothelial cells (Yanagisawa et al., 1988). Endothelin receptors can be classified as subtype A (ET-A) and subtyp...
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Chapter
Functional Markers for Fetal and Postnatal Differentiation of Rat Leydig Cells
The aim of the present work was to establish morphological markers for the functional differentiation of Leydig cells in rat in order to study the origin, development and maturation of these cells. Two differe...
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Chapter
Expression of VEGF and its Receptors and Capillary Density in Leydig Cell Tumors of the Human Testis
A close association can be observed between the Leydig cells and the capillaries of normal human testis (Ergün et al., 1996). A prerequisite for tumor growth is neoangiogenesis (Folkman, 1982). One of the angi...
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Chapter
Morphological and Functional Aspects of the Human Spermatic Cord Veins
It is well known that varicocele of the testis may lead to a damage of testicular tissue and therefore is one etiologic factor for male infertility. Successful varicocele treatment may result in preserving or ...
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Chapter
VEGF Modulates the Capillaries of the Human Epididymis
Vascular endothelial growth factor (VEGF), a high specific endothelial cell mitogen (Conn et al., 1990), stimulates angiogenesis and enhances endothelial permeability by fenestration of venular and capillary e...
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Chapter
Microcirculation and the Vascular Control of the Testis
The arterial blood supply of the human testicular parenchyma within a testicular lobule demonstrates a segmental organization. In correlation to Leydig cells and seminiferous tubules within such a testicular t...