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Natural history and noninvasive of diagnosis of subpulmonic ventricular septal defect

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  1. Chapter

    Fetal and Neonatal Ductus Arteriosus Is Regulated with ATP-Sensitive Potassium Channel

    The fetal patency and neonatal closure of the ductus arteriosus (DA) are regulated with oxygen and prostaglandins. The proposed oxygen sensors of fetal and neonatal DA include P450-endothelin and the Kv channe...

    Kazuo Momma, Mika Monma, Katsuaki Toyoshima… in Etiology and Morphogenesis of Congenital H… (2016)

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  2. Chapter and Conference Paper

    Dilatation of the Ductus Arteriosus by Diazoxide in Fetal and Neonatal Rats

    We previously reported that ATP-sensitive potassium (KATP) channels regulate ductal constriction in response to oxygen [1]. Diazoxide is a KATP channel opener while the usefulness of diazoxide for hyperinsulinemi...

    Katsuaki Toyoshima, Kazuo Momma… in Molecular Mechanism of Congenital Heart Di… (2020)

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  3. Chapter and Conference Paper

    Constriction of the Ductus Arteriosus with KATP Channel Inhibitors

    The cause of fetal death by sulfonylureas (SUs), used for diabetes in pregnancy in the early 1960s, remained unsolved for decades. In 1993, Nakanishi discovered constriction of ductus arteriosus (DA) strips in...

    Kazuo Momma, Katsuaki Toyoshima… in Molecular Mechanism of Congenital Heart Di… (2020)

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