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    Chapter

    Impact of Localized Microwave Hyperthermia on the Oxygenation Status of Malignant Tumors

    Considerable insight into the mechanisms of heat induced cell death in vitro has been gained during recent years (for reviews see 1–3). Besides the direct cell killing effect of heat, many microenvironmental or m...

    J. Otte, R. Manz, G. Thews, P. Vaupel in Hyperthermia (1982)

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    Chapter

    Preoperative and Postoperative Intensive Care and Oedema Therapy

    78% of our child patients with brain tumours showed signs of raised intracerebral pressure on first admission to the department. They were thus endangered patients who require subtle diagnosis. We should like ...

    J. Otte, P. Emmrich, G. Meinig in Tumours of the Central Nervous System in I… (1982)

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    Chapter

    Relationship Between Size and Oxygenation Status of Malignant Tumors

    During advanced phases of malignant growth, there are typical changes in the microvasculature pattern within the tissue of many solid tumors. Partly due to these peculiarities of tumor vascularization, a serie...

    R. Manz, J. Otte, G. Thews, P. Vaupel in Oxygen Transport to Tissue—IV (1983)

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    Chapter

    Effect of Localized Hyperthermia on Tumor Blood Flow and Oxygenation

    Hyperthermia has been shown to have a lethal effect in tumor cell cultures, particularly at temperatures above 42°C.1 Moreover, it has been demonstrated that hyperthermia retards the growth rate of certain types ...

    W. Mueller-Klieser, R. Manz, J. Otte, P. Vaupel in Recent Advances in Medical Thermology (1984)

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    Chapter

    Impact of Various Thermal Doses on the Oxygenation and Blood Flow in Malignant Tumors Upon Localized Hyperthermia

    Hyperthermia exhibits various direct cytocidal effects (Dickson, 1977; Overgaard, 1977; Suit, 1977). During heat treatment in vivo, several indirect mechanisms enhance the direct cell-killing capa...

    P. Vaupel, W. Müller-Klieser, J. Otte, R. Manz in Oxygen Transport to Tissue-V (1984)