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    ACTH Precursors in Different Pathological Conditions

    ACTH is synthesised as part of a 31kD, pro-hormone, proopiomelano — cortin (POMC), and the processing of POMC is tightly regulated in a tissue specific manner. The POMC processing pathway (seeFigure 1) has been b...

    Anne White, David Ray in The Acth Axis: Pathogenesis, Diagnosis and Treatment (2003)