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    Chapter

    Macrophages as an Important Source of Paracrine IL6 in Myeloma Bone Marrow

    Interleukin 6 (IL6) is a pleiotropic cytokine which has been shown to be a very potent growth factor for myeloma cells, particularly cells derived from patients with aggressive clinical disease (1,2). Although it...

    Brian G. M. Durie, Elizabeth E. Vela… in Mechanisms in B-Cell Neoplasia 1990 (1990)

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    Chapter

    Workshop on growth factors

    The ‘Workshop on Growth Factors’ which took place at the Lugano Lymphoma Conference on June 8, 1990, included a presentation by Michael Sporn on the concept that loss of inhibitory control mechanisms may be im...

    Professor Derek Crowther, Michael B. Sporn, Anita B. Roberts… in Annals of Oncology (1991)

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    Chapter and Conference Paper

    Cytogenetic Abnormalities in Multiple Myeloma

    Cytogenic studies in multiple myeloma have been very difficult because of the predominantly low proliferative activity in this disease (1-7). In the series reported to date the most commonly affected chromosomes ...

    Brian G. M. Durie, Elizabeth E. Vela… in Epidemiology and Biology of Multiple Myelo… (1991)

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    Chapter

    The Role of Anatomic and Functional Imaging in Myeloma

    Brian G.M. Durie in Myeloma Therapy (2008)