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    Chapter

    Oxidative Injury Caused by Cigarette Smoking and Air Pollution

    Oxidative stress is pivotal to the biological effects, tissue injury, and disease following exposures to both cigarette smoke and air pollutants. Cigarette smoke and air pollutants can directly generate oxidan...

    Andrew J. Ghio in Studies on Respiratory Disorders (2014)

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    Chapter

    Pneumoconiosis in the Twenty-First Century

    While defined pathologically, it is uncommon that the diagnosis of pneumoconiosis necessitates tissue biopsy. The approach initially used by physicians for diagnosis of asbestosis has been extrapolated to all ...

    Andrew J. Ghio in A Clinical Guide to Occupational and Environmental Lung Diseases (2012)

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    Chapter

    Relative Intrinsic Potency of Asbestos and Erionite Fibers: Proposed Mechanism of Action

    Data from human exposure to naturally occurring mineral fibers indicates extreme variability in the rate of mesothelioma between various asbestos varieties and erionite. Experiments on rats have confirmed thes...

    David L. Coffin, Andrew J. Ghio in Mechanisms in Fibre Carcinogenesis (1991)