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The transition from tube feeding to oral feeding algorithm in preterm infants: case-control study
BackgroundOral feeding is a complex sensorimotor process influenced by many variables, making it challenging for healthcare providers to introduce...
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Assessing the suitability of video-assisted anal fistula treatment for obese patients compared to conventional surgery: a question worth investigating
Background and aimsVideo-assisted anal fistula treatment (VAAFT) is an innovative surgical approach enabling the direct visualization of the fistula...
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SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study
A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate...
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Map** alternative splicing events in colorectal cancer
Although aberrant splicing events of genes are closely related to the development and progression of colorectal cancer (CRC), the map** of abnormal...
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Lessons from the physiological role of guanosine in neurodegeneration and cancer: Toward a multimodal mechanism of action?
Neurodegenerative diseases and brain tumours represent important health challenges due to their severe nature and debilitating consequences that...
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Coronary periarteritis and pericarditis are rare but distinct manifestations of heart involvement in IgG4-related disease: a retrospective cohort study
BackgroundThe heart can be involved in immunoglobulin (Ig)-G4-related disease (IgG4-RD). This study aimed to summarize the clinical features and...
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Autoantibodies Neutralizing GM-CSF in HIV-Negative Colombian Patients Infected with Cryptococcus gattii and C. neoformans
BackgroundCryptococcosis is a life-threatening disease caused by Cryptococcus neoformans or C. gattii . Neutralizing autoantibodies (auto-Abs)...
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Influence of Urolithin A and Cholecalciferol on IFN-γ Production by Peripheral Blood Mononuclear Cells Under Normal Conditions and in the Presence of Products Released by Tumor Cells
Urolithin A is a polyphenolic metabolite of ellagic acid and ellagitannins that is produced by intestinal microbiota and has higher bioavailability...
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Die Psyche atmet mit
BackgroundIn addition to significant physical limitations, individuals with interstitial lung diseases (ILD) often experience reduced quality of life...
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Association of cord blood Ang-1 and sCD105 levels with bronchopulmonary dysplasia in preterm infants
BackgroundTo investigate the relationship between cord blood levels of Angiopoietin-1 (Ang-1) and S-endoglin (sCD105) and bronchopulmonary dysplasia...
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Phytochemical Analysis of Extract and Essential Oil of Echinophora platyloba
Echinophora platyloba DC. is one of the two exclusive species from Iran belonging to the Umbelliferae family. This plant has medicinal properties...
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Design, Synthesis and Biological Evaluation of (Z)-1-(Benzo[D]Thiazol-2-yl)-2-(3-Substituted Thiazolidine-4-One) Hydrazine Dpre1 Inhibitors as Antimycobacterial Agents
A simple and promising methodology was employed for the synthesis of (Z )-1-(benzo[ d ]thiazol-2-yl)-2-(3-substituted thiazolidine-4-one) hydrazine as...
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A novel class of indole derivatives: enhanced bioavailability, permeability, and antioxidant efficacy for thromboembolic disease therapy
Free radicals like reactive oxygen species (ROS) and reactive nitrogen species (RNS) cause cellular damage and contribute to thromboembolic diseases...
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Pharmacodynamic Comparison of Two Aspirin Formulations in the Caribbean: The ARC Study
IntroductionThis prospective, single-arm, crossover pharmacodynamic study assessed the effect of Bayer ® low-dose enteric-coated aspirin 81 mg...
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Mavorixafor: First Approval
Mavorixafor (XOLREMDI™) is an oral, selective C-X-C chemokine receptor 4 (CXCR4) antagonist developed by X4 Pharmaceuticals that blocks the binding...
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Detection and characterization of autoreactive memory stem T-cells in children with acute immune thrombocytopenia
Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by an isolated decrease in platelets below 100 × 10 9 /l after...
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Efficacy and Safety of Salvage-line Nivolumab Monotherapy for Advanced Esophageal Squamous Cell Carcinoma: Comparison of 240 mg Versus 480 mg Doses
BackgroundNivolumab monotherapy is the standard second-line treatment for advanced esophageal squamous cell carcinoma (ESCC) after failure of...
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Effect of dorsal capsular imbrication on intraoperative DRUJ instability following arthroscopic TFCC repair surgery
BackgroundTo assess the clinical outcomes and identify the ideal indication for implementing dorsal distal radioulnar joint (DRUJ) capsular...