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Emodin alleviates intestinal ischemia–reperfusion injury through antioxidant stress, anti-inflammatory responses and anti-apoptosis effects via Akt-mediated HO-1 upregulation
BackgroundIntestinal ischemia–reperfusion (I/R) injury is a severe vascular emergency. Previous research indicated the protective effects of Emodin...
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New studies with stable gastric pentadecapeptide protecting gastrointestinal tract. significance of counteraction of vascular and multiorgan failure of occlusion/occlusion-like syndrome in cytoprotection/organoprotection
Since the early 1990s, when Robert’s and Szabo’s cytoprotection concept had already been more than one decade old, but still not implemented in...
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Neglected but Clinically Relevant Allergens in Korea
Purpose of ReviewAllergy diagnostics and immunotherapeutics in Asia heavily rely on imported products from Western countries, raising concerns about...
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Protective effects of ginsenosides on ulcerative colitis: a meta-analysis and systematic review to reveal the mechanisms of action
BackgroundUlcerative colitis (UC) is a chronic inflammatory disease of the colon. Ginsenoside may be an ideal agent for UC treatment. However, its...
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Variability in Alternaria alternata spore characteristics under different culture conditions: implications for automatic detection using air flow cytometry
Airborne fungal spores of the genus Alternaria pose challenges for accurate airborne spore identification by automatic bioaerosol monitors, because...
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Protective and curative effects of unconjugated bilirubin on gene expression of LOX-1 and iNOS in the heart of rats receiving high-fat diet and low dose streptozotocin: a histomorphometric approach
BackgroundAtherosclerosis is a chronic inflammatory condition affecting the large arteries and is a major cause of cardiovascular diseases (CVDs)...
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Gut microbiota regulation of T lymphocyte subsets during systemic lupus erythematosus
BackgroundSystemic lupus erythematosus (SLE) is an autoimmune disease characterized by disturbance of pro-inflammatory and anti-inflammatory...
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Food-Pollen Cross-Reactivity and its Molecular Diagnosis in China
Purpose of ReviewPlant-derived foods are one of the most common causative sources of food allergy in China, with a significant relationship to...
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Buckwheat Allergy in Asia
Purpose of ReviewBuckwheat (BW) allergy is a significant issue in Asia. This review delves into three types of BW allergy: immediate food allergy;...
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LCP1 correlates with immune infiltration: a prognostic marker for triple-negative breast cancer
ObjectiveTriple-Negative Breast Cancer (TNBC) is known for its aggressiveness and treatment challenges due to the absence of ER, PR, and HER2...
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Association of HLA-G 3′UTR polymorphisms with hepatitis B virus infection in Tunisian population
Hepatitis B virus (HBV) infection is a major public health burden. The mechanisms of immune evasion during chronic HBV (CHB) infection are poorly...
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Human ADA2 Deficiency: Ten Years Later
Purpose of ReviewIn this review, an update is provided on the current knowledge and pending questions about human adenosine deaminase type 2...
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Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections
Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, modulate immune cell functions, particularly macrophages. This review...
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Elastin-derived peptides (EDPs) as a potential pro-malignancy factor in human leukemia cell lines
AbstractThe extracellular matrix (ECM) is currently considered to be an important factor influencing the migration and progression of cancer cells....
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Kinin B1 receptor and TLR4 interaction in inflammatory response
ObjectiveWe aimed to broaden our understanding of a potential interaction between B1R and TLR4, considering earlier studies suggesting that...
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Chemical composition and studying the possible neuroprotective effect of iridoids-rich fraction from Pentas lanceolata leaves using rotenone model of Parkinson’s disease in mice
Parkinsonism is an age-related neurodegenerative illness that affects motor coordination leading to loss of dopaminergic neurons. Many medications...
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Workup and Management of Immunodeficiency in Chronic Rhinosinusitis
Chronic rhinosinusitis (CRS), especially if severe, recurrent, or refractory to standard medical management, should prompt consideration of an...
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NLRP3 (rs10754558) gene polymorphism and tumor necrosis factor alpha as predictors for disease activity and response to methotrexate and adalimumab in psoriasis
BackgroundPsoriasis has a global prevalence of 1–3%, with variations observed across different ethnic groups and geographical areas. Disease...
