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Clinical features and underlying etiology of children with Lennox–Gastaut syndrome
ObjectiveLennox–Gastaut Syndrome (LGS) is characterized by the presence of multiple seizure types and encompasses a heterogenous group of etiologies....
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A Translational Approach to Using Endocannabinoid Modulators for Targeting Opioid-Associated Memory
Purpose of ReviewIt is well established that learning and memory are central to substance dependence. Convincing basic and clinical documents...
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Circular walking is useful for assessing the risk of falls in early progressive supranuclear palsy
BackgroundProgressive supranuclear palsy (PSP) is characterized by early onset postural instability and frequent falls. Circular walking necessitates...
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Digital outcome measures are associated with brain atrophy in patients with multiple sclerosis
BackgroundDigital monitoring of people with multiple sclerosis (PwMS) using smartphone-based monitoring tools is a promising method to assess disease...
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Critical Care of Spinal Cord Injury
Purpose of ReviewSpinal cord injury (SCI) is a major cause of morbidity and mortality, posing a significant financial burden on patients and the...
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Progressive multifocal leukoencephalopathy and spectrum of predisposing conditions: a 20-year retrospective cohort study in a tertiary center in São Paulo, Brazil
BackgroundEpidemiological studies on predisposing conditions and outcomes of progressive multifocal leukoencephalopathy (PML) cases have been carried...
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Embelin Mitigates Amyloid-β-Induced Neurotoxicity and Cognitive Impairment in Rats: Potential Therapeutic Implications for Alzheimer’s Disease
Alzheimer’s disease (AD) is a significant form of dementia. Embelin (EMB) is a natural compound with varied actions that could help prevent AD...
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Intracranial Pressure Thresholds for Cerebral Autoregulation Impairment: Age-Stratified Analysis of Ultra-Low-Frequency Pressure Reactivity Index (UL-PRx) in Traumatic Brain Injury
BackgroundThe study investigated the effectiveness of low-frequency sampling in detecting alterations in cerebrovascular reactivity (CVR) associated...
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Therapeutic potential of transient receptor potential (TRP) channels in psychiatric disorders
Psychiatric disorders such as Bipolar disorder, Anxiety, Major depressive disorder, Schizophrenia, Attention-deficit/hyperactivity disorder, as well...
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FABP3 Induces Mitochondrial Autophagy to Promote Neuronal Cell Apoptosis in Brain Ischemia-Reperfusion Injury
This study elucidates the molecular mechanisms by which FABP3 regulates neuronal apoptosis via mitochondrial autophagy in the context of cerebral...
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The developmental phenotype of motor delay in extremely preterm infants following early-life respiratory adversity is influenced by brain dysmaturation in the parietal lobe
BackgroundResearch indicates that preterm infants requiring prolonged mechanical ventilation often exhibit suboptimal neurodevelopment at follow-up,...
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Rheumatoid meningitis in the absence of rheumatoid arthritis: 2 cases
Rheumatoid meningitis (RM) is a rare extra-articular manifestation of rheumatoid arthritis (RA) that has been increasingly recognized by...
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High blood glucose variability may predict poor outcomes in patients with spontaneous cerebellar hemorrhage undergoing surgical operation: a retrospective study
BackgroundElevated blood glucose (BG) variability has been reported as an independent risk factor for poor prognosis in a variety of diseases. This...
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Treatment with robot-assisted gait trainer Walkbot along with physiotherapy vs. isolated physiotherapy in children and adolescents with cerebral palsy. Experimental study
BackgroundImproving walking ability is a key objective in the treatment of children and adolescents with cerebral palsy, since it directly affects...
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DBScope as a versatile computational toolbox for the visualization and analysis of sensing data from deep brain stimulation
Different neurostimulators for deep brain stimulation (DBS) come already with the ability to chronically sense local field potentials during...
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SDS3 regulates microglial inflammation by modulating the expression of the upstream kinase ASK1 in the p38 MAPK signaling pathway
BackgroundMicroglia, the main innate immune cells in the central nervous system, are key drivers of neuroinflammation, which plays a crucial role in...
