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Interrelationship between thyroid hormones and reduced renal function, a review article
BackgroundUnderstanding the relationship of thyroid hormones with the development of chronic kidney disease (CKD) has important clinical implications...
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Effect of recurrent severe insulin-induced hypoglycemia on the cognitive function and brain oxidative status in the rats
BackgroundEpisodes of recurrent or severe hypoglycemia can occur in patients with diabetes mellitus, insulinoma, neonatal hypoglycemia, and...
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Safety and Psychological Outcomes of Tandem t:Slim X2 Insulin Pump with Control-IQ Technology in Children, Adolescents, and Young Adults with Type 1 Diabetes: A Systematic Review
The Tandem t:slim X2 insulin pump is a second-generation automated insulin delivery system with Control-IQ technology. It consists of an X2 insulin...
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Tirzepatide Improved Health-Related Quality of Life Compared with Insulin Lispro in Basal Insulin-Treated Adults with Type 2 Diabetes and Inadequate Glycaemic Control: A Randomised Controlled Phase 3b Trial (SURPASS-6)
IntroductionPatients with type 2 diabetes (T2D) who require intensification of basal insulin therapy need treatment options that can improve their...
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Diaph1 knockout inhibits mouse primordial germ cell proliferation and affects gonadal development
BackgroundExploring the molecular mechanisms of primordial germ cell (PGC) migration and the involvement of gonadal somatic cells in gonad...
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Association of Changes in A1C Following Continuous Glucose Monitoring Acquisition in People with Sub-Optimally Treated Type 2 Diabetes Taking GLP-1 RA Therapy
IntroductionBoth glucagon-like peptide-1 receptor agonists (GLP-1 RA) and continuous glucose monitoring (CGM) improve glycemia in patients with type...
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3Dimensional sonography for the diagnosis of congenital uterine anomalies in women with eccentric pregnancy implantation: a novel approach
PurposeThe eccentric implantation of pregnancies in the upper lateral aspect of the uterine cavity is poorly defined clinically. The aim of the...
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The challenges of assessing adiposity in a clinical setting
To tackle the burden of obesity-induced cardiometabolic disease, the scientific community relies on accurate and reproducible adiposity measurements...
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Predictors of response to Radioactive Iodine Therapy in Intermediate and high risk patients with papillary thyroid carcinoma
BackgroundRadioactive iodine (RAI) therapy is the standard treatment approach after total thyroidectomy in patients with papillary thyroid carcinoma...
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Assessment of glycemic susceptibility across multiple urological and reproductive disorders
ObjectiveTo test the glycemic susceptibility in three urological cancers and eight urological/reproductive diseases using the Mendelian randomization...
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ISIS 449884 Injection Add-On to Metformin in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Study
IntroductionISIS 449884, a 2′- O -methoxyethyl antisense oligonucleotide that targets the glucagon receptor (GCGR), has demonstrated an ability to...
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Comparison of clinical characteristics and treatment outcomes between initially diagnosed type 1 and type 2 diabetes mellitus patients presenting with diabetic ketoacidosis
ObjectivePatients with type 1 diabetes (T1DM) and type 2 diabetes (T2DM) can present with diabetic ketoacidosis (DKA) as the first manifestation....
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A comparison of brown fat tissue related hormone levels in metabolically healthy and unhealthy individuals with obesity
PurposeOne of the key functions of brown adipose tissue is its positive impact on metabolism. This study aimed to examine the potential involvement...
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The association between waist-to-hip ratio (WHR) with diabetes in the PERSIAN Guilan cohort study population
BackgroundWaist circumference (WC), or waist-to-hip ratio (WHR), potentially offers a more accurate reflection of intra-abdominal fat accumulation...
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Multiple collapses of blastocysts after full blastocyst formation is an independent risk factor for aneuploidy — a study based on AI and manual validation
BackgroundThe occurrence of blastocyst collapse may become an indicator of preimplantation embryo quality assessment. It has been reported that...
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Effective strategies for pregnancy and lactation-associated osteoporosis: teriparatide use in focus
IntroductionPregnancy and lactation-associated osteoporosis (PLO) is a rare condition characterized by fragility fractures occurring during late...
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Very Low Calorie Ketogenic Diet: What Effects on Lipid Metabolism?
Purpose of ReviewThis review aims to critically examine how VLCKD affects plasma lipoprotein, lipid and cholesterol metabolism. Cardiovascular...
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Low fetal fraction and adverse pregnancy outcomes— systematic review of the literature and metanalysis
PurposeWhile cell-free DNA (cfDNA) screening has emerged as a screening modality for common aneuploidies, further research and several publications...
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Thyroid complications after hemopoietic stem cell transplantation in children and adolescents
PurposeTo evaluate the prevalence of thyroid dysfunction and its association with possible contributing factors related to diagnosis and treatment in...
