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Pipette-tip solid-phase extraction coupled with matrix-assisted laser desorption/ionization mass spectrometry enables rapid and high-throughput analysis of antidepressants in rat serum
Therapeutic drug monitoring is essential for ensuring the efficacy and safety of medications. This study introduces a streamlined approach that...
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GC × GC-HRMS with complementary ionization methods in the suspect screening analysis of fragrance allergens: overwhelming or justified?
Modern gas chromatography-mass spectrometry (GC–MS) allows for the analysis of complex samples, such as fragrances. However, identifying all the...
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Structural characterization, atomic Hirshfeld surface analysis, thermal behavior, electric and vibrational studies of the new tellurate conductor material
In the current research work, we investigated the growth of the new potassium arsenate tellurate material formulated as K 2 (HAsO 4 ).Te(OH) 6 (KAsTe)...
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Evaluation of the stabilizing effect and ageing time indicator properties of poly(flavonoids) in a cyclic olefin copolymer
Few studies are concerned with the stabilization of polymers using natural polymeric polyphenols. There are no literature reports on the use of...
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Multiple comparisons of acetylene black–based rigid composite electrodes: comprehensive evaluation of chemical properties and electrochemical sensing potentialities
We report the comparison of multiple acetylene black (AB) rigid carbon composites for electrochemical purposes exploring several binders, including...
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Green Extraction of Anthocyanins from Prunus domestica Using Natural Deep Eutectic Solvents: Anti-sickling Properties and Phenolic Impact Assessment
Natural Deep Eutectic Solvents (NADESs) are a form of green solvents used to extract phenolic compounds and are considered a more environmentally...
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New Frontiers on Intracellular cGAS Activation: Molecular Mechanisms, Cellular Signaling, and Therapeutic Strategies
Cyclic GMP-AMP (cGAMP) synthase (cGAS) plays a pivotal role in the innate immune system. As the primary DNA sensor in cells, cGAS binds to dsDNA in...
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[H2dab][GaB5O10]: an Acentric Galloborate with a 4-Connected Uninodal Framework
A new acentric galloborate (GBO) [H 2 dab][GaB 5 O 10 ] ( 1 , 1,4-dab: 1,4-diaminobutane) has been synthesized under solvothermal conditions. The alternation...
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Exploring the Predominant Factors Influencing the Oxygen Reduction Performance of PtCo/C Catalysts
PtCo nanoalloys (NAs) deposited on carbon black are emerging as robust electrocatalysts for addressing the sluggish kinetic issue of oxygen reduction...
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A Scalable Pillar Layered Metal-Organic Framework for Natural Gas Purification
One-step harvest of high-purity methane (CH 4 ) from ternary propane/ethane/methane (C 3 H 8 /C 2 H 6 /CH 4 ) mixtures remains a desirable yet challenging goal...
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A stochastic approach for parameter optimization of feature detection algorithms for non-target screening in mass spectrometry
Feature detection plays a crucial role in non-target screening (NTS), requiring careful selection of algorithm parameters to minimize false positive...
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Insights into the thermochemistry of paracetamol in ternary mixtures of eutectic solvents
Solution enthalpies of paracetamol, Δ sol H , in choline chloride–ethylene glycol–water mixtures were evaluated at 298.15 K. Solvatochromic UV–vis...
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Submersible voltammetric sensing probe for rapid and extended remote monitoring of opioids in community water systems
The intensifying global opioid crisis, majorly attributed to fentanyl (FT) and its analogs, has necessitated the development of rapid and...
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Structure Engineering of Layered Double Hydroxides (LDHs) for Heterogeneous Catalysis
Layered double hydroxide (LDH) is regarded as an advanced platform material in catalysis and attracts vast attrition recently. As a kind of...
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Development of a supramolecular solvent–based extraction method for application to quantitative analyses of a wide range of organic contaminants in indoor dust
This study investigates the efficacy of supramolecular solvent (SUPRAS) in extracting a diverse spectrum of organic contaminants from indoor dust....
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Progress, applications, and challenges in high-throughput effect-directed analysis for toxicity driver identification — is it time for HT-EDA?
The rapid increase in the production and global use of chemicals and their mixtures has raised concerns about their potential impact on human and...
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Reaction Kinetics and Secondary Organic Aerosol Composition Analysis of 2-Cyclohexen-1-one with NO3 Radicals
Unsaturated ketones are typical oxygenated volatile organic compounds (OVOCs) with high reactivity, and are important precursors in air pollution....
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Quantitative comparison of bile acid glucuronides sub-metabolome between intrahepatic cholestasis and healthy pregnant women
Because of the pathological indication and the physiological functions, bile acids (BAs) have occupied the research hotspot in recent decades....
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Fluorescent DNA tetrahedral probe with catalytic hairpin self-assembly reaction for imaging of miR-21 and miR-155 in living cells
A CHA-based fluorescent DNA tetrahedral probe (FDTp) has been designed to detect the microRNAs miR-21 and miR-155 sensitively and specifically in...
