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Exploring the potential of Lactocaseibacillus rhamnosus PMC203 in inducing autophagy to reduce the burden of Mycobacterium tuberculosis
Mycobacterium tuberculosis , a lethal pathogen in human history, causes millions of deaths annually, which demands the development of new concepts of...
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ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer’s disease mouse model
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer’s disease (AD). Aberrations in GABAergic function and the...
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Fitness costs of Tn1546-type transposons harboring the vanA operon by plasmid type and structural diversity in Enterococcus faecium
BackgroundThis study analyzed the genetic traits and fitness costs of vancomycin-resistant Enterococcus faecium (VREfm) blood isolates carrying Tn 1546...
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Drug-induced ER stress leads to induction of programmed cell death pathways of the malaria parasite
The rapid emergence of drug resistance against the mainstream antimalarial drugs has increased the need for development of novel drugs. Recent...
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Update on the Regulation and Maintenance of Epstein-Barr Virus Latency
Purpose of ReviewAs the first identified human oncogenic virus, Epstein-Barr virus (EBV) is widely circulating in humans. EBV presents mainly in...
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A novel betapartitivirus isolated from Cordyceps militaris, an edible-medicinal mushroom
In this study, we identified a novel partitivirus, named "Cordyceps militaris partitivirus 1" (CmPV1), in Cordyceps militaris strain RCEF7506. The...
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New Variants Identified by Next-Generation Sequencing in Polycystic Kidney Disease Patients
Polycystic kidney disease (PKD) is a common inherited disease characterized by multiple cysts in kidneys and various extra renal manifestations....
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Human cytomegalovirus microRNAs: strategies for immune evasion and viral latency
Viruses use various strategies and mechanisms to deal with cells and proteins of the immune system that form a barrier against infection. One of...
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Cultivation of novel Atribacterota from oil well provides new insight into their diversity, ecology, and evolution in anoxic, carbon-rich environments
BackgroundThe Atribacterota are widely distributed in the subsurface biosphere. Recently, the first Atribacterota isolate was described and the...
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Impact of the COVID-19 pandemic on extended-spectrum β-lactamase producing Escherichia coli in urinary tract and blood stream infections: results from a nationwide surveillance network, Finland, 2018 to 2022
BackgroundBefore the COVID-19 pandemic there has been a constant increase in antimicrobial resistance (AMR) of Escherichia coli , the most common...
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GIS-based spatiotemporal map** of malaria prevalence and exploration of environmental inequalities
Malaria poses a significant threat to global health, with particular severity in Nigeria. Understanding key factors influencing health outcomes is...
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A randomised trial of malaria vaccine R21/Matrix-M™ with and without antimalarial drugs in Thai adults
In preparation for mass vaccinations with R21/Matrix-M™ combined with mass administrations of dihydroartemisinin, piperaquine, and a single low dose...
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Development and validation of machine learning models to predict MDRO colonization or infection on ICU admission by using electronic health record data
BackgroundMultidrug-resistant organisms (MDRO) pose a significant threat to public health. Intensive Care Units (ICU), characterized by the extensive...
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Secondary attack rate following on-site isolation of patients with suspected COVID-19 in multiple-bed rooms
The implementation of isolation precautions for patients with suspected Coronavirus Disease 2019 (COVID-19) and pending test results is resource...
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CircFAM114A2 Suppresses Cell Proliferation, Migration, and Invasion of Colorectal Cancer Through Sponging miR-647 to Upregulate DAB2IP Expression
BackgroundIncreasing evidence had proved that some circular RNA (circRNA) exerted critical roles in tumors progression by functioning as “microRNAs...
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Evaluation of the in vitro activity of ampicillin-sulbactam and cefoperazone-sulbactam against A. Baumannii by the broth disk elution test
To evaluate the in vitro activity of ampicillin-sulbactam and cefoperazone-sulbactam against A. baumannii using the broth disk elution testing, a...
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Fecal microbiota transplantation alters gut phage communities in a clinical trial for obesity
BackgroundFecal microbiota transplantation (FMT) is a therapeutic intervention used to treat diseases associated with the gut microbiome. In the...
