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Open AccessAcquired resistance to immunotherapy in MMR-D pancreatic cancer
MMR-D pancreatic cancer have been reported to respond to checkpoint inhibitor therapy. Here, we report the first case of acquired resistance to immunotherapy in MMR-D pancreatic cancer.
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Open AccessImmunotherapy in Breast Cancer: the New Frontier
This review summarizes current immunotherapies in breast cancer, with an emphasis on immune checkpoint inhibitors and vaccines.
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Erratum: Targeting RET-driven cancers: lessons from evolving preclinical and clinical landscapes
Nature Reviews Clinical Oncology http://dx.doi.org/10.1038/nrclinonc.2017.175 (2017) In the online and PDF versions of this Review, in the 'Acquired resistance' subsection, RETI788N was erroneously written as ...
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Targeting RET-driven cancers: lessons from evolving preclinical and clinical landscapes
Activating alterations of the RET kinase are therapeutically actionable oncogenic drivers across a variety of cancers; in-frame RET rearrangements occur in sub...
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Open AccessThe Abscopal Effect of Radiation Therapy: What Is It and How Can We Use It in Breast Cancer?
The abscopal effect refers to the ability of localized radiation to trigger systemic antitumor effects. Over the past 50 years, reports on the abscopal effect arising from conventional radiation have been rela...