57 Result(s)
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Article
Zhong** Yang
Cell Biology
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Article
Molecular cloning and characterization of Ct-PKAR, a gene encoding the regulatory subunit of cAMP-dependent protein kinase in Colletotrichum trifolii
Colletotrichum trifolii is a plant pathogenic fungus causing alfalfa anthracnose. Prepenetration development, including conidial germination and appressorial formation, are requisite for...
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Identity, distribution, and development of polydendrocytes: NG2-expressing glial cells
Cells that express the NG2 proteoglycan (NG2+ cells) comprise a unique population of glial cells in the central nervous system. While there is no question that some NG2+ cells differentiate into oligodendrocyt...
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Effects of chloride and potassium channel blockers on apoptotic cell shrinkage and apoptosis in cortical neurons
K+ and Cl− homeostasis have been implicated in cell volume regulation and apoptosis. We addressed the hypothesis that K+ and Cl− efflux may contribute to apoptotic cell shrinkage and apoptotic death in cultured c...
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Fine map** of an Arabidopsis thaliana male sterile mutant EC2-157
An Arabidopsis thaliana male sterile mutant EC2-157 has been isolated using an EMS mutagenesis strategy. Genetic analysis indicated that it was controlled by a single recessive gene called ms157. No pollen grains...
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Differences on Pb accumulation among plant tissues of 25 varieties of maize (Zea mays)
Pollution of agricultural land by heavy metals has imposed an increasingly serious risk to environmental and human health in recent years. Heavy metal pollutants may enter the human food chain through agricult...
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Erythropoietin Prevents Blood Brain Barrier Damage Induced by Focal Cerebral Ischemia in Mice
Recombinant human erythropoietin (rhEPO), a neurovascular protective agent, therapeutically supports angiogenesis after stroke by enhancing endogenous up-regulation of vascular endothelial growth factor (VEGF)...
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Induction, selection and antibacterial activity of the antibacterial peptides from lepidopteran insect cultured cell lines
We induced 3 cell lines that were in vitro cultured from Lepidoptera with heat inactivated Escherichia coli DH5α to stimulate the antibacterial peptide followed by antibacterial activity assay, induction dynamic ...
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Critical effect of VEGF in the process of endothelial cell apoptosis induced by high glucose
The underlying molecular mechanism whereby hyperglycemia causes endothelial cell apoptosis is not well understood. This study aims to elucidate the role of survival factor VEGF involved in the apoptosis of end...
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Cadmium and copper uptake and accumulation by Sesbania rostrata seedling, a N-fixing annual plant: implications for the mechanism of heavy metal tolerance
Sesbania rostrata, an annual tropical legume, has been found to be tolerant to heavy metals, with an unknown mechanism. It is a promising candidate species for revegetation at mine tailings. In this study, sequen...
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Two new cell lines originated from the embryos of Clostera anachoreta (Lepidoptera: Notodontidae): characterization and susceptibility to baculoviruses
Two cell lines designated CAF-Clan I and CAF-Clan II have been established from embryos of Clostera anachoreta (Lepidoptera: Notodontidae) in TNM-FH medium containing 10% inactivated fetal bovine serum. CAF-Clan ...
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In vivo selection of tumor-targeting RNA motifs
Successive rounds of selection of an RNA library in a mouse cancer model resulted in the identification of an aptamer that specifically bound a cancer-associated protein, providing an in vivo approach for identif...
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Plasminogen K5 activates mitochondrial apoptosis pathway in endothelial cells by regulating Bak and Bcl-xL subcellular distribution
Plasminogen Kringle 5(K5) is a proteolytic fragment of plasminogen, which displays potent anti-angiogenic activities. K5 has been shown to induce apoptosis in proliferating endothelial cells; however the exact...
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Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger
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Open AccessSubepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries
Coronary arteries bring blood flow to the heart muscle. Understanding the developmental program of the coronary arteries provides insights into the treatment of coronary artery diseases. Multiple sources have ...
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Introduction to Deep Sequencing and Its Application to Drug Addiction Research with a Focus on Rare Variants
Through linkage analysis, candidate gene approach, and genome-wide association studies (GWAS), many genetic susceptibility factors for substance dependence have been discovered such as the alcohol dehydrogenas...
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Characterization of a Putative Stereoselective Oxidoreductase from Gluconobacter oxydans and Its Application in Producing Ethyl (R)-4-Chloro-3-Hydroxybutanoate Ester
A gene encoding an NADH-dependent short-chain dehydrogenase/reductase (gox2036) from Gluconobacter oxydans 621H was cloned and heterogeneously expressed in Escherichia coli. The protein (Gox2036) was purified to...
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Open AccessInhibiting CCN1 blocks AML cell growth by disrupting the MEK/ERK pathway
CCN1 plays distinct roles in various tumor types, but little is known regarding the role of CCN1 in leukemia.
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Dystrophin Involved in the Susceptibility of Slow Muscles to Hindlimb Unloading via Concomitant Activation of TGF-β1/Smad3 Signaling and Ubiquitin–Proteasome Degradation in Mice
While it is well known that the slow-twitch muscles are vulnerable to microgravity conditions, the molecular and cellular mechanisms underlying this phenomenon remain unknown. Dystrophin, which constitutes an ...
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Open AccessGenetic deletion of IL-25 (IL-17E) confers resistance to dextran sulfate sodium-induced colitis in mice
IL-25 is emerging as a key regulator of inflammation in the intestinal mucosa because of its ability to promote type 2 while suppressing Th1 and Th17 responses. Several previous studies reported inconsistent r...
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Involvement of sulfhydryl compounds and antioxidant enzymes in H2S-induced heat tolerance in tobacco (Nicotiana tabacum L.) suspension-cultured cells
Hydrogen sulfide (H2S) is a multifunctional second messenger involved in plant growth, development, and acquisition of stress tolerance, including heat tolerance, but the mechanism of H2S-induced heat tolerance i...
