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  1. Article

    Open Access

    Human embryonic stem cell-derived retinal pigment epithelium transplants as a potential treatment for wet age-related macular degeneration

    Stem cell therapy may provide a safe and promising treatment for retinal diseases. Wet age-related macular degeneration (wet-AMD) is a leading cause of blindness in China. We developed a clinical-grade human e...

    Yong Liu, Hai Wei Xu, Lei Wang, Shi Ying Li, Cong Jian Zhao, Jie Hao… in Cell Discovery (2018)

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  2. Article

    Open Access

    Long-term safety of human retinal progenitor cell transplantation in retinitis pigmentosa patients

    Retinitis pigmentosa is a common genetic disease that causes retinal degeneration and blindness for which there is currently no curable treatment available. Vision preservation was observed in retinitis pigmen...

    Yong Liu, Shao Jun Chen, Shi Ying Li, Ling Hui Qu… in Stem Cell Research & Therapy (2017)

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  3. Article

    Open Access

    Grafted c-kit+/SSEA1− eye-wall progenitor cells delay retinal degeneration in mice by regulating neural plasticity and forming new graft-to-host synapses

    Despite diverse pathogenesis, the common pathological change observed in age-related macular degeneration and in most hereditary retinal degeneration (RD) diseases is photoreceptor loss. Photoreceptor replacem...

    ** Chen, Zehua Chen, Zhengya Li, Chen Zhao, Yuxiao Zeng… in Stem Cell Research & Therapy (2016)

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