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  1. Article

    Open Access

    Notch signaling mutations increase intra-tumor chemokine expression and predict response to immunotherapy in colorectal cancer

    The Notch signaling mutation is associated with enhanced anti-tumor immune response in colorectal cancer (CRC). In this study, we aim to investigate the underlying mechanism and the predictive potential of Not...

    Fei Wang, Chuan Huang, Jie Long, Zhi-Bin Zhao, Hai-Qing Ma, Xue-Qing Yao… in BMC Cancer (2022)

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  2. No Access

    Article

    Replication study and meta-analysis indicate a suggestive association of RUNX3 locus with primary biliary cholangitis

    Susceptibility to primary biliary cholangitis (PBC) is in part genetically determined. In our previous PBC genome-wide association study (GWAS) in 1118 Han Chinese PBC and 4036 controls, we noted that multiple...

    Rohil Jawed, Mingming Zhang, Chan Wang, Shu-Han Yang, Peng Jiang… in Immunogenetics (2020)

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    Article

    Liver-resident NK cells suppress autoimmune cholangitis and limit the proliferation of CD4+ T cells

    Liver-resident NK cells are distinct from conventional NK cells and play an important role in the maintenance of liver homeostasis. How liver-resident NK cells participate in autoimmune cholangitis remains unc...

    Zhi-Bin Zhao, Fang-Ting Lu, Hong-Di Ma, Yin-Hu Wang… in Cellular & Molecular Immunology (2020)

  4. No Access

    Article

    Creation of a rabbit model for intrauterine adhesions using electrothermal injury

    The pathogenesis and therapeutic treatment of intrauterine adhesions (IUAs) remain unsolved, highlighting the need for stable and effective experimental animal models. In this study, uterine electrocoagulation...

    **n-xin Xu, Lian-bao Cao, Zhe Wang, Zhen Xu… in Journal of Zhejiang University-SCIENCE B (2018)

  5. No Access

    Article

    Association of genetic polymorphisms of interleukins with gastric cancer and precancerous gastric lesions in a high-risk Chinese population

    Helicobacter pylori (H. pylori) infection and cytokine-mediated inflammatory responses play important roles in gastric cancer (GC) pathogenesis. To investigate an association between gene...

    Yu-Mei Wang, Zhe-Xuan Li, Fu-Bing Tang, Yang Zhang, Tong Zhou, Lian Zhang… in Tumor Biology (2016)

  6. No Access

    Article

    Comparative Proteomics Analysis of Cerebrospinal Fluid of Patients with Guillain–Barré Syndrome

    To better understand the pathophysiologic mechanisms underlying Guillain–Barré syndrome (GBS), Comparative proteomic analysis of cerebrospinal fluid (CSF) between patients with GBS (the experiment group) and c...

    Yin-Rong Yang, Shi-Lian Liu, Zhao-Yu Qin, Fu-Jun Liu… in Cellular and Molecular Neurobiology (2008)