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Open AccessSpecific Mode Electroacupuncture Stimulation Mediates the Delivery of NGF Across the Hippocampus Blood–Brain Barrier Through p65-VEGFA-TJs to Improve the Cognitive Function of MCAO/R Convalescent Rats
Cognitive impairment frequently presents as a prevalent consequence following stroke, imposing significant burdens on patients, families, and society. The objective of this study was to assess the effectivenes...
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Open AccessAuthor Correction: Design of robotic arm for the porcelain bushing in substation
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Open AccessThe UF-5000 Atyp.C parameter is an independent risk factor for bladder cancer
Bladder carcinoma (BC) accounts for > 90% of all urothelial cancers. Pathological diagnosis through cytoscopic biopsy is the gold standard, whereas non-invasive diagnostic tools remain lacking. The “Atyp.C” pa...
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Article
Open AccessExtrachromosomal circular DNA (eccDNA): from carcinogenesis to drug resistance
Extrachromosomal circular DNA (eccDNA) is a circular form of DNA that exists outside of the chromosome. Although it has only been a few decades since its discovery, in recent years, it has been found to have a...
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Open AccessResearch on fault identification of high-voltage circuit breakers with characteristics of voiceprint information
High voltage circuit breakers are one of the core equipment in power system operation, and the voiceprint signals generated during operation contain extremely rich information. This paper proposes a fault iden...
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Open AccessDesign of robotic arm for the porcelain bushing in substation
With the development and the application popularization of artificial intelligence robot technology and 5G technology, a robotic arm is designed and developed for rinsing porcelain bushing in high voltage subs...
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Article
Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system
Short prokaryotic Ago accounts for most prokaryotic Argonaute proteins (pAgos) and is involved in defending bacteria against invading nucleic acids. Short pAgo associated with TIR-APAZ (SPARTA) has been shown ...
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Open AccessFailure mode and effects analysis using an improved pignistic probability transformation function and grey relational projection method
Failure mode and effects analysis (FMEA) is an important risk analysis tool that has been widely used in diverse areas to manage risk factors. However, how to manage the uncertainty in FMEA assessments is stil...
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Open AccessFriction injury of the central vein caused by catheter for hemodialysis: an in vitro study
Vascular injury such as central venous stenosis (CVS) is a common complication in hemodialysis patients with central venous catheters (CVCs), yet the impact of the microstructure and partial physic characteris...
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Open AccessSTK3 kinase activation inhibits tumor proliferation through FOXO1-TP53INP1/P21 pathway in esophageal squamous cell carcinoma
Esophageal squamous cell carcinoma (ESCC) is an aggressive disease with a poor prognosis, caused by the inactivation of critical cell growth regulators that lead to uncontrolled proliferation and increased mal...
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Open AccessAnalysis of heterologous expression of phaCBA promotes the acetoin stress response mechanism in Bacillus subtilis using transcriptomics and metabolomics approaches
Acetoin, a versatile platform chemical and popular food additive, poses a challenge to the biosafety strain Bacillus subtilis when produced in high concentrations due to its intrinsic toxicity. Incorporating the ...
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Open AccessTRPM8 inhibits substance P release from primary sensory neurons via PKA/GSK-3beta to protect colonic epithelium in colitis
Transient receptor potential melastatin 8 (TRPM8) is a cold sensory receptor in primary sensory neurons that regulates various neuronal functions. Substance P (SP) is a pro-inflammatory neuropeptide secreted b...
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The Relationship Between Perceived Childhood Harsh Parental Discipline and Cyberbullying among College Students: A Moderated Mediation Model
According to the dynamic cascade model of development, the present study explored the effect mechanism of the relationship between perceived childhood harsh parental discipline, deviant peer affiliation, core ...
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Open AccessSim-GAIL: A generative adversarial imitation learning approach of student modelling for intelligent tutoring systems
The continuous application of artificial intelligence (AI) technologies in online education has led to significant progress, especially in the field of Intelligent Tutoring Systems (ITS), online courses and le...
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Safety and efficacy of laparoscopic transperitoneal versus retroperitoneal resection for benign retroperitoneal tumors: a retrospective cohort study
Benign retroperitoneal tumors (BRTs) are clinically rare solid tumors. This study aimed to compare the safety and efficacy of laparoscopic transperitoneal versus retroperitoneal resection for BRTs.
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Can maternal involvement protect children from bullying victimization when fathers migrate for work? A serial mediation model
Lack of parental care is one of the potential causes of bullying victimization of left-behind children (LBC) in China. In father-absent families, maternal involvement may be a protective factor against peer bu...
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Open AccessIdentification of a c-type heme oxygenase and its function during acclimation of cyanobacteria to nitrogen fluctuations
The mechanisms of acclimating to a nitrogen-fluctuating environment are necessary for the survival of aquatic cyanobacteria in their natural habitats, but our understanding is still far from complete. Here, th...
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The influences of natural structure damage and stress path on mechanical behaviors of soft clay
This work aims to investigate the influence of structural damage to natural soft clay on its mechanical behavior. K0 consolidated triaxial tests with loading and unloading stress paths were conducted, and field e...
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Amine-functionalized cellulose nanofiber-sodium alginate-Fe(III) porous hollow beads for the efficient removal of Cr(VI)
To date, highly toxic heavy metal ions from wastewater seriously deteriorate the aquatic environment safety. This study proposes an adsorbent that can be adopted to remove heavy metal ions by combining environ...
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Open AccessTargeting IGF1R signaling enhances the sensitivity of cisplatin by inhibiting proline and arginine metabolism in oesophageal squamous cell carcinoma under hypoxia
Cisplatin (DDP)-based chemotherapy is commonly adopted as the first-line treatment for patients with oesophageal squamous cell carcinoma (OSCC), but the high rate of drug resistance limits its clinical applica...