35 Result(s)
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Article
Yun Kwok Wing
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Open AccessChronic post-COVID neuropsychiatric symptoms persisting beyond one year from infection: a case-control study and network analysis
Our study aims to delineate the phenotypes of chronic neuropsychiatric symptoms among adult subjects recovering from their first COVID that occurred more than one year ago. We also aim to explore the clinical ...
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Open AccessAssociations between obesity, a composite risk score for probable long COVID, and sleep problems in SARS-CoV-2 vaccinated individuals
Preliminary data suggests that obesity might hasten the decline in mRNA vaccine-induced immunity against SARS-CoV-2. However, whether this renders individuals with obesity more susceptible to long COVID sympto...
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Open AccessEffects of cognitive behavioural therapy and bright light therapy for insomnia in youths with eveningness: study protocol for a randomised controlled trial
Insomnia and eveningness are common and often comorbid conditions in youths. While cognitive behavioural therapy for insomnia (CBT-I) has been suggested as a promising intervention, it remains unclear whether ...
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Open AccessMultimodal digital assessment of depression with actigraphy and app in Hong Kong Chinese
There is an emerging potential for digital assessment of depression. In this study, Chinese patients with major depressive disorder (MDD) and controls underwent a week of multimodal measurement including actig...
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Open AccessThe Impact of Social Media Use on Sleep and Mental Health in Youth: a Sco** Review
Social media use (SMU) and other internet-based technologies are ubiquitous in today’s interconnected society, with young people being among the commonest users. Previous literature tends to support that SMU i...
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Open AccessEstimation bias and agreement limits between two common self-report methods of habitual sleep duration in epidemiological surveys
Accurate measurement of habitual sleep duration (HSD) is crucial for understanding the relationship between sleep and health. This study aimed to assess the bias and agreement limits between two commonly used ...
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Open AccessAssociations between changes in habitual sleep duration and lower self-rated health among COVID-19 survivors: findings from a survey across 16 countries/regions
Self-rated health (SRH) is widely recognized as a clinically significant predictor of subsequent mortality risk. Although COVID-19 may impair SRH, this relationship has not been extensively examined. The prese...
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Open AccessGut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives
The microbiota-gut-brain axis has been suggested to play an important role in Parkinson’s disease (PD). Here we performed a cross-sectional study to profile gut microbiota across early PD, REM sleep behavior d...
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Open AccessAssociation of accelerometer-derived circadian abnormalities and genetic risk with incidence of atrial fibrillation
Evidence suggests potential links between circadian rhythm and atrial fibrillation (AF). However, whether circadian disruption can predict the onset of AF in the general population remains largely unknown. We ...
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Validation of the Revised Illness Perception Questionnaire of Obstructive Sleep Apnea among Elderly Chinese in the General Population
The prevalence of under-diagnosis among individuals with obstructive sleep apnea (OSA) is alarming, and may be associated with perceptions regarding OSA. To facilitate future studies on OSA, this study validat...
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Open AccessAssociations of timing of physical activity with all-cause and cause-specific mortality in a prospective cohort study
There is a growing interest in the role of timing of daily behaviors in improving health. However, little is known about the optimal timing of physical activity to maximize health benefits. We perform a cohort...
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Open AccessAssociation between sleep duration and metabolic syndrome: linear and nonlinear Mendelian randomization analyses
Observational studies have found that both short and long sleep duration are associated with increased risk of metabolic syndrome (MetS). This study aimed to examine the associations of genetically determined ...
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Open AccessPersistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals
Short nighttime sleep duration impairs the immune response to virus vaccination, and long nighttime sleep duration is associated with poor health status. Thus, we hypothesized that short (<6 h) and long (>9 h)...
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Open AccessThe interplay of acute cortisol response and trait affectivity in associating with stress resilience
Resilience is the cornerstone to mental health, and entails multiple biological and psychological mechanistic processes. However, the interplay of the psychobiological processes in sha** resilience is unclea...
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Open AccessAntibody stabilization for thermally accelerated deep immunostaining
Antibodies have diverse applications due to their high reaction specificities but are sensitive to denaturation when a higher working temperature is required. We have developed a simple, highly scalable and ge...
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Open AccessPersonality profile and its association with conversion to neurodegenerative disorders in idiopathic REM sleep behavior disorder
Patients with Parkinson’s disease (PD) were described less extraverted and more neurotic. It remained unclear whether similar personality traits could be found in idiopathic rapid eye movement sleep behavior d...
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Open AccessPromoting physical activity and health in Hong Kong primary school children through a blended physical literacy intervention: protocol and baseline characteristics of the “Stand+Move” randomized controlled trial
Children predominantly remain sedentary in a traditional classroom. This study aimed to demonstrate the design and baseline characteristics of a three-armed intervention program that targeted enhancements in c...
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Open AccessSystemic GLP-1R agonist treatment reverses mouse glial and neurovascular cell transcriptomic aging signatures in a genome-wide manner
Pharmacological reversal of brain aging is a long-sought yet challenging strategy for the prevention and treatment of age-related neurodegeneration, due to the diverse cell types and complex cellular pathways ...
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The association between high risk of sleep apnea, comorbidities, and risk of COVID-19: a population-based international harmonized study
Obstructive sleep apnea (OSA) may increase the risk of severe COVID-19; however, the level of potential modulation has not yet been established. The objective of the study was to determine the association betw...
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Non-pharmacological Approaches for Management of Insomnia
Insomnia is a prevalent sleep problem associated with a constellation of negative health-related outcomes and significant socioeconomic burden. It commonly co-occurs with psychiatric and medical conditions, wh...
