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  1. Article

    Open Access

    Conditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis

    Mesenchymal stem cells (MSCs) can improve cutaneous wound healing via the secretion of growth factors. However, the therapeutic efficacy of MSCs varies depending upon their source. Induced pluripotent stem cel...

    **aoting Liang, Fang Lin, Yue Ding, Yuelin Zhang, Mimi Li in Stem Cell Research & Therapy (2021)

  2. Article

    Open Access

    Inhibition of miR-199a-5p rejuvenates aged mesenchymal stem cells derived from patients with idiopathic pulmonary fibrosis and improves their therapeutic efficacy in experimental pulmonary fibrosis

    Idiopathic pulmonary fibrosis (IPF) is an age-related disease with no cure. Mesenchymal stem cell (MSC)-based therapy has emerged as a novel strategy for IPF treatment. Nevertheless, MSCs derived from patients...

    Linli Shi, Qian Han, Yimei Hong, Weifeng Li, Gencheng Gong in Stem Cell Research & Therapy (2021)

  3. No Access

    Article

    Exosomes: Cell-Free Therapy for Cardiovascular Diseases

    Cardiovascular diseases (CVDs) are an important cause of death and disease worldwide. Because injured cardiac tissue cannot be repaired itself, it is urgent to develop other alternate therapies. Stem cells can...

    Nana He, Yuelin Zhang, Shun Zhang in Journal of Cardiovascular Translational Re… (2020)

  4. Article

    Open Access

    Potent immunomodulation and angiogenic effects of mesenchymal stem cells versus cardiomyocytes derived from pluripotent stem cells for treatment of heart failure

    Optimal cell type as cell-based therapies for heart failure (HF) remains unclear. We sought to compare the safety and efficacy of direct intramyocardial transplantation of human embryonic stem cell-derived car...

    Songyan Liao, Yuelin Zhang, Sherwin Ting, Zhe Zhen, Fan Luo in Stem Cell Research & Therapy (2019)