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  1. Article

    Open Access

    Myosteatosis as a prognostic factor of Mycobacterium avium complex pulmonary disease

    Quantitative body composition affects the prognosis of patients with Mycobacterium avium complex pulmonary disease (MAC-PD). However, whether the qualitative body composition obtained indirectly through computed ...

    Eunki Chung, Youngmok Park, Song Yee Kim, Moo Suk Park, Young Sam Kim in Scientific Reports (2023)

  2. Article

    Open Access

    Long-term clinical course and progression of lymphangioleiomyomatosis in a single lung transplant referral centre in Korea

    We aimed to describe the clinical features of lymphangioleiomyomatosis (LAM) in Korean patients and identify factors associated with progressive disease (PD). Clinical features of 54 patients with definite or ...

    Shihwan Chang, Ji Soo Choi, Ah Young Leem, Su Hwan Lee, Sang Hoon Lee in Scientific Reports (2022)

  3. Article

    Open Access

    Thoracic skeletal muscle quantification using computed tomography and prognosis of elderly ICU patients

    In elderly ICU patients, the prevalence of skeletal muscle loss is high. Longitudinal effect of thoracic muscles, especially in elderly ICU patients, are unclear although skeletal muscle loss is related with t...

    Sung Woo Moon, Song Yee Kim, Ji Soo Choi, Ah Young Leem, Su Hwan Lee in Scientific Reports (2021)

  4. Article

    Open Access

    Impact of non-cystic fibrosis bronchiectasis on critically ill patients in Korea: a retrospective observational study

    This study investigated the impact of bronchiectasis on patients admitted to the intensive care unit (ICU) at a hospital in Korea. Patients with bronchiectasis were diagnosed using results of chest computed to...

    Youngmok Park, Seung Hyun Yong, Ah Young Leem, Song Yee Kim in Scientific Reports (2021)

  5. Article

    Open Access

    Corticosteroid responsiveness in patients with acute exacerbation of interstitial lung disease admitted to the emergency department

    Interstitial lung disease (ILD), particularly idiopathic pulmonary fibrosis (IPF), has a poor prognosis. Corticosteroids are widely used in the treatment of acute exacerbation of ILD (AE-ILD). This study aimed...

    Hye ** Jang, Seung Hyun Yong, Ah Young Leem, Su Hwan Lee in Scientific Reports (2021)

  6. Article

    Open Access

    Correlation between serum carbohydrate antigen 19-9 levels and computed tomography severity score in patients with nontuberculous mycobacterial pulmonary disease

    There is no validated clinical biomarker for disease severity or treatment response for nontuberculous mycobacterial pulmonary disease (NTM-PD). We investigated the correlation between elevated serum carbohydr...

    Kangjoon Kim, Seung Hyun Yong, Su Hwan Lee, Sang Hoon Lee in Scientific Reports (2021)

  7. Article

    Open Access

    Efficacy of low dose pirfenidone in idiopathic pulmonary fibrosis: real world experience from a tertiary university hospital

    Pirfenidone is an antifibrotic agent that has been proven to slow down the progression of idiopathic pulmonary fibrosis (IPF). The aim of this study was to evaluate the efficacy of low-dose pirfenidone (that i...

    Myung ** Song, Sung Woo Moon, Ji Soo Choi, Sang Hoon Lee in Scientific Reports (2020)

  8. Article

    Open Access

    Diagnosis and mortality prediction of sepsis via lysophosphatidylcholine 16:0 measured by MALDI-TOF MS

    Sepsis remains a critical problem with high mortality worldwide, but there is still a lack of reliable biomarkers. We aimed to evaluate the serum lysophosphatidylcholine (LPC) 16:0 as a biomarker of sepsis usi...

    Eun Hye Lee, Mi Hwa Shin, Jong-Min Park, Sang-Guk Lee, Nam Su Ku in Scientific Reports (2020)

  9. Article

    Open Access

    Low serum lymphocyte level is associated with poor exercise capacity and quality of life in chronic obstructive pulmonary disease

    The purpose of this study was to evaluate the association of serum lymphocyte level with several clinical parameters in COPD. The study population included 451 COPD patients from the Korean Obstructive Lung Di...

    Sung Woo Moon, Ah Young Leem, Young Sam Kim, Ji-Hyun Lee in Scientific Reports (2020)

  10. Article

    Open Access

    The optimal sequence of bronchial brushing and washing for diagnosing peripheral lung cancer using non-guided flexible bronchoscopy

    The optimum sequence of bronchial brushing and washing for diagnosing peripheral lung cancer, defined as an invisible endobronchial tumour, is not clear and requires further study. We prospectively obtained wa...

    Jun Hyeok Lim, Min Jeong Kim, Sang-Hoon Jeon, Mi Hwa Park in Scientific Reports (2020)

  11. Article

    Open Access

    Longitudinal decline in lung function: a community-based cohort study in Korea

    Progressive decline in lung function is the hallmark of chronic obstructive pulmonary disease (COPD). We aimed to assess the rate of decline in forced expiratory volume in 1 second (FEV1) in patients from a commu...

    Ah Young Leem, Boram Park, Young Sam Kim, Joon Chang, Sungho Won in Scientific Reports (2019)

  12. Article

    Open Access

    Optimal timing of initiating continuous renal replacement therapy in septic shock patients with acute kidney injury

    Acute kidney injury (AKI) in patients with septic shock is associated with high mortality, but the appropriate timing for initiating continuous renal replacement therapy (CRRT) is controversial. We retrospecti...

    Bo Ra Yoon, Ah Young Leem, Moo Suk Park, Young Sam Kim in Scientific Reports (2019)

  13. Article

    Open Access

    Risk factors and clinical characteristics of Pneumocystis jirovecii pneumonia in lung cancer

    Solid malignancies are associated with the development of Pneumocystis jirovecii pneumonia (PJP). This study aimed to evaluate the risk factors for PJP among patients with lung cancer. This retrospective case-con...

    Eun Hye Lee, Eun Young Kim, Sang Hoon Lee, Yun Ho Roh, Ah Young Leem in Scientific Reports (2019)

  14. Article

    Open Access

    Changes in cytokine responses to TB antigens ESAT-6, CFP-10 and TB 7.7 and inflammatory markers in peripheral blood during therapy

    Multiple cytokines and inflammatory markers control TB infection. We aimed to investigate the changes in multiple cytokines and inflammatory markers in active TB patients following anti-TB drug therapy. Twenty...

    Ah Young Leem, Joo Han Song, Eun Hye Lee, Hyejon Lee, Bora Sim in Scientific Reports (2018)

  15. Article

    Open Access

    Clinical implications of the plasma EphA2 receptor level in critically ill patients with septic shock

    The Eph/ephrin receptor ligand system is known to play a role in inflammation induced by infection, injury, and inflammatory diseases. The present study aimed to evaluate plasma EphA2 receptor levels in critic...

    Su Hwan Lee, Ju Hye Shin, Joo Han Song, Ah Young Leem, Moo Suk Park in Scientific Reports (2017)

  16. Article

    Open Access

    Active Tuberculosis Incidence and Characteristics in Patients Treated with Tumor Necrosis Factor Antagonists According to Latent Tuberculosis Infection

    This study aimed to determine the incidence and characteristics of active tuberculosis (TB) in patients treated with tumor necrosis factor (TNF) antagonists according to baseline latent tuberculosis infection ...

    Eun Hye Lee, Young Ae Kang, Ah Young Leem, Moo Suk Park in Scientific Reports (2017)

  17. Article

    Open Access

    Risk factors for Pneumocystis jirovecii pneumonia (PJP) in kidney transplantation recipients

    Pneumocystis jirovecii pneumonia (PJP) is a potentially life-threatening infection that occurs in immunocompromised patients. The aim of this study was to evaluate risk factors for PJP in...

    Su Hwan Lee, Kyu Ha Huh, Dong ** Joo, Myoung Soo Kim, Soon Il Kim in Scientific Reports (2017)