16 Result(s)
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Article
Yinsheng Zhang
English
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Article
Open AccessA Georeferenced Dataset for Map** and Assessing Subgrade Defects in China’s High-Speed Railways
China has the world’s longest high-speed rail (HSR) network, marked by dense transportation and complex operations. However, frequent train use coupled with extreme weather conditions has led to rising subgrad...
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Open AccessMulti-defect risk assessment in high-speed rail subgrade infrastructure in China
This study addresses the escalating risk of high-speed railway (HSR) infrastructure in China, amplified by climate warming, increased rainfall, frequent extreme weather, and geohazard events. Leveraging a geor...
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Runoff modelling and quantification of supraglacial debris impact on seasonal streamflow in the highly glacierized catchments of the western Karakoram in Upper Indus Basin, Pakistan
A precise estimation of seasonal runoff and accurate quantification of discharge components is imperative for understanding the hydroclimatic regimes in mountainous regions. This study aimed to investigate dai...
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A unified classifiability analysis framework based on meta-learner and its application in spectroscopic profiling data
Spectroscopic profiling data (e.g., Raman spectroscopy and mass spectroscopy), combined with machine learning, have provided a data-driven approach for discriminative tasks. In these tasks, researchers often s...
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Shifting from homogeneous to heterogeneous surfaces in estimating terrestrial evapotranspiration: Review and perspectives
Terrestrial evapotranspiration (ET) is a crucial link between Earth’s water cycle and the surface energy budget. Accurate measurement and estimation remain a major challenge in geophysical, biological, and env...
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Ground observed climatology and trend in snow cover phenology across China with consideration of snow-free breaks
Accurate understanding of snow cover phenology and its changes is important to hydrological processes and climate system. Having recognized the potential uncertainties in remote sensing snow cover products, we...
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Synthesis of deuterium-labeled nelarabine and its active ingredient, ara-G
Nelarabine is a prodrug of the deoxyguanosine analogue, 9-β-D-arabinofuranose guanine (ara-G), which is used for the treatment of patients with T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblas...
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Open AccessPost-20th century near-steady state of Batura Glacier: observational evidence of Karakoram Anomaly
Stable or marginal mass loss dominating in Karakoram has been reported widely through satellite and ground investigations. This work aimed to verify the variation in glacier mass by collecting ground-based dat...
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Augmented anti-tumor activity of NK-92 cells expressing chimeric receptors of TGF-βR II and NKG2D
The capacity of natural killer (NK) cells to kill tumor cells without specific antigen recognition provides an advantage over T cells and makes them potential effectors for tumor immunotherapy. However, the ef...
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Spatiotemporal variations of actual evapotranspiration over the Lake Selin Co and surrounding small lakes (Tibetan Plateau) during 2003–2012
Actual evapotranspiration (ET a ) over the Tibetan Plateau (TP) is an important component of the water cycle, and greatly influences the water bu...
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Open AccessA concise drug alerting rule set for Chinese hospitals and its application in computerized physician order entry (CPOE)
A minimized and concise drug alerting rule set can be effective in reducing alert fatigue.
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Open AccessAn activation-induced IL-15 isoform is a natural antagonist for IL-15 function
Interleukin 15 (IL-15) expression induces the secretion of inflammatory cytokines, inhibits the apoptosis of activated T cells and prolongs the survival of CD8+ memory T cells. Here we identified an IL-15 isoform...
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Hydrological regimes under the conjunction of westerly and monsoon climates: a case investigation in the Astore Basin, Northwestern Himalaya
In a changing climate, river basins with limited summer precipitation but abundant snow and glacier melt-water are affected severely by reductions and seasonal alterations in annual stream flows. However, high...
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Plateau Wetlands, an Indispensible Habitat for the Black-Necked Crane (Grus nigricollis) - A Review
As a highly productive and sensitive ecosystem, plateau wetlands provide indispensable habitats for Grus nigricollis, an endangered species of crane. However, the destruction and degeneration of plateau wetlands ...
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Facile syntheses of isotope-labeled chiral octahydroindole-2-carboxylic acid and its N-methyl analog
We have synthesized deuterium and carbon-14 labeled enantiomerically pure octahydroindole-2-carboxylic acid (PD0140417), N-methyl octahydroindole-2-carboxylic acid (PD0348183) and their racemic analogs (PD0108405...
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Clinical significance of circulating tumor cells in breast cancer patients
Circulating tumor cells (CTCs) are defined as tumor cells circulating in the peripheral blood of patients, shed from either the primary tumors or its metastases. Many techniques have been developed in the rece...
