43 Result(s)

Article

The impact of diet, exercise, and sleep on Helicobacter pylori infection with different occupations: a cross-sectional study

Associations between Helicobacter pylori infection and lifestyle factors vary greatly by geographic location. This study aims to evaluate the prevalence of Helicobacter pylori infection in the Hunan cohort of cen...

Shiwen He, Xue He, Yinglong Duan, Yating Luo, Yuxuan Li, **g Li… in BMC Infectious Diseases (2024)

Article

Strategies for the development and approval of COVID-19 vaccines and therapeutics in the post-pandemic period

The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in significant casualties and put immense strain on public health systems worldwide, leading to economic recession and so...

Danyi Ao, Xuemei He, Jian Liu, Li Xu in Signal Transduction and Targeted Therapy (2023)

Article

JMJD6 in tumor-associated macrophage regulates macrophage polarization and cancer progression via STAT3/IL-10 axis

The tumor-associated macrophage (TAM) is the most abundant group of immune cells in the tumor microenvironment (TME), which plays a critical role in the regulation of tumor progression and treatment resistance...

Siyuan Chen, Manni Wang, Tianqi Lu, Yu Liu, Weiqi Hong, Xuemei He, Yuan Cheng… in Oncogene (2023)

Article

Pharmacokinetics and Safety of iGlarLixi in Healthy Chinese Participants: Results of a Phase 1 Randomized Study

The Chinese Diabetes Society recommends basal insulin and glucagon-like peptide-1 receptor agonists as an add-on therapy to first-line oral antihyperglycemic drugs for people with type 2 diabetes (T2D). Fixed-...

Panpan **e, Xuemei He, **n Gao, Mengmeng Shuai, Wolfgang Schmider… in Diabetes Therapy (2023)

Article

Vaccine adjuvants: mechanisms and platforms

Adjuvants are indispensable components of vaccines. Despite being widely used in vaccines, their action mechanisms are not yet clear. With a greater understanding of the mechanisms by which the innate immune r...

Tingmei Zhao, Yulong Cai, Yujie Jiang… in Signal Transduction and Targeted Therapy (2023)

Article

PMN-MDSCs modulated by CCL20 from cancer cells promoted breast cancer cell stemness through CXCL2-CXCR2 pathway

Our previous studies have showed that C-C motif chemokine ligand 20 (CCL20) advanced tumor progression and enhanced the chemoresistance of cancer cells by positively regulating breast cancer stem cell (BCSC) s...

Rui Zhang, Mengxue Dong, Juchuanli Tu… in Signal Transduction and Targeted Therapy (2023)

Article

Efficacy of tolvaptan in postoperative volume therapy for acute Stanford type A aortic dissection

Despite the increasing application of tolvaptan in cardiac surgery, there is no information on the use of tolvaptan in Stanford patients with type A aortic dissection. This study aimed to evaluate the postoper...

Wenjun Wang, Feng Gao, Xuezhi He, Yang Gao, Lei Shi… in BMC Cardiovascular Disorders (2023)

Article

The predictive value of pulmonary function test before transplantation for chronic pulmonary graft-versus-host-disease after allogeneic hematopoietic stem cell transplantation

Pulmonary chronic graft-versus-host disease (cGVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a devastating complication and often diagnosed at a late stage when lung dysfunction ...

Lingyi Yang, Jia Cheng, Fei Li, Ruiqi Qian, **uqin Zhang… in BMC Pulmonary Medicine (2022)

Article

Intranasal administration of a recombinant RBD vaccine induces long-term immunity against Omicron-included SARS-CoV-2 variants

The outbreak of coronavirus disease 2019 (COVID-19) has posed great threats to global health and economy. Several effective vaccines are available now, but additional booster immunization is required to retain...

Hong Lei, Aqu Alu, **gyun Yang, Wenyan Ren… in Signal Transduction and Targeted Therapy (2022)

Article

Spike protein of SARS‐CoV‐2 Omicron (B.1.1.529) variant has a reduced ability to induce the immune response

Cai He, Xuemei He, **gyun Yang, Hong Lei… in Signal Transduction and Targeted Therapy (2022)

Article

Long noncoding RNA MALAT1 polymorphism predicts MACCEs in patients with myocardial infarction

Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) participates in the occurrence and development of cardiovascular and cerebrovascular diseases such as stroke and coronary heart disease by regula...

Tong Zhang, Jun-Yi Luo, Fen Liu, Xue-He Zhang, Fan Luo… in BMC Cardiovascular Disorders (2022)

Article

miR-93-5p suppresses ovarian cancer malignancy and negatively regulate CCND2 by binding to its 3′UTR region

Ovarian cancer is the most fatal gynecological cancer worldwide, yet the fundamental mechanism of malignancy acquisition in ovarian cancer remains unknown. miRNA has been implicated to a variety of diseases, i...

Guotong Chen, Yiwei Yan, **aojv Qiu, Chengfeng Ye, **ngmei Jiang… in Discover Oncology (2022)

Article

Correction to: Identifying Parkinson’s disease with mild cognitive impairment by using combined MR imaging and electroencephalogram

A Correction to this paper has been published: https://doi.org/10.1007/s00330-021-07757-5

Jiahui Zhang, Yuyuan Gao, Xuetao He, Shujun Feng, **long Hu… in European Radiology (2022)