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Article
Open AccessGenerating diverse clothed 3D human animations via a generative model
Data-driven garment animation is a current topic of interest in the computer graphics industry. Existing approaches generally establish the map** between a single human pose or a temporal pose sequence, and ...
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Article
Open AccessEmbryonic exposure to ethanol increases the susceptibility of larval zebrafish to chemically induced seizures
Prenatal ethanol exposure is known to cause neurodevelopmental disorders. While high prevalence of epilepsy is observed among the children whose mothers abused alcohol during pregnancy, the results from animal...
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Article
Open AccessActivation of autophagy attenuates EtOH-LPS-induced hepatic steatosis and injury through MD2 associated TLR4 signaling
Autophagy serves as a protective mechanism to degrade damaged organelles and proteins. Acute alcohol exposure is known to activate the hepatic autophagy response, whereas chronic alcohol exposure slows autopha...
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Article
Open AccessFibroblast growth factor 21 deficiency exacerbates chronic alcohol-induced hepatic steatosis and injury
Fibroblast growth factor 21 (FGF21) is a hepatokine that regulates glucose and lipid metabolism in the liver. We sought to determine the role of FGF21 in hepatic steatosis in mice exposed to chronic alcohol tr...
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Article
Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway
This study investigated fibroblast growth factor 21 (FGF21)-mediated cardiac protection against apoptosis caused by diabetic lipotoxicity and explored the protective mechanisms involved.
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Open AccessFibroblast growth factor 21 deletion aggravates diabetes-induced pathogenic changes in the aorta in type 1 diabetic mice
Fibroblast growth factor 21 (FGF21) is an important regulator in glucose and lipid metabolism, and has been considered as a potential therapy for diabetes. The effect of FGF21 on the development and progressio...
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Article
Expression and Purification of Human Keratinocyte Growth Factor 2 by Fusion with SUMO
Small ubiquitin-related modifier (SUMO) fusion system has been shown to be efficient for enhancing expression and preventing degradation of the target protein. We showed herein that SUMO fusion to human kerati...
