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Open AccessBispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
Anti-multiple myeloma B cell maturation antigen (BCMA)-specific chimeric antigen receptor (CAR) T-cell therapies represent a promising treatment strategy with high response rates in myeloma. However, durable c...
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Article
Open AccessTargeting Aspergillus allergen oryzin with a chemical probe at atomic precision
We report the molecular basis of Aspergillus fumigatus oryzin, allergen Asp f 13, or alkaline proteinase ALP1, containing the sequence motif His–Asp–Ser of the subtilisin family, structure, and function at atomic...
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Article
Open AccessDegradation of 1-alkyl-3-methylimidazolium tetrafluoroborate in an ultrasonic zero-valent zinc and activated carbon micro-electrolysis system
Increased attention has been given to the removal of ionic liquids (ILs) from natural water environments. In this work, 5 kinds of 1-alkyl-3-methylimidazoliumtetrafluoroborate ([Cnmim][BF4] (n = 2, 4, 6, 8, 10)) ...
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Open AccessGenome-wide transcriptome analysis of the orphan crop tef (Eragrostis tef (Zucc.) Trotter) under long-term low calcium stress
Calcium (Ca2+) is one of the essential mineral nutrients for plant growth and development. However, the effects of long-term Ca2+ deficiency in orphan crops such as Tef [(Eragrostis tef) (Zucc.) Trotter], which a...
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Open AccessSelf-sustained electricity generator driven by the compatible integration of ambient moisture adsorption and evaporation
Generating sustainable electricity from ambient humidity and natural evaporation has attracted tremendous interest recently as it requires no extra mechanical energy input and is deployable across all weather ...
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Article
Potent antitumor activity of novel taxoids in anaplastic thyroid cancer
Anaplastic thyroid cancer (ATC) is the most aggressive form of thyroid cancers and it is rapidly fatal without any effective therapeutic regimens. There are some clinical trials showing that paclitaxel-based c...
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Article
Open AccessKinetic photovoltage along semiconductor-water interfaces
External photo-stimuli on heterojunctions commonly induce an electric potential gradient across the interface therein, such as photovoltaic effect, giving rise to various present-day technical devices. In cont...
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Article
Mesoscopic Analysis of the Mechanical Properties of Beishan Granite Based on the Equivalent Crystal Model
The internal microstructure of rock has an important influence on its macroscopic mechanical properties and fracture mechanism. In this paper, an equivalent crystal model (ECM) consisting of a bonded particle ...
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Open AccessHigh-frequency rectifiers based on type-II Dirac fermions
The advent of topological semimetals enables the exploitation of symmetry-protected topological phenomena and quantized transport. Here, we present homogeneous rectifiers, converting high-frequency electromagn...
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Open AccessDistinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly become a global public health threat. The efficacy of several repurposed dr...
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Open AccessSingle-site pyrrolic-nitrogen-doped sp2-hybridized carbon materials and their pseudocapacitance
Integrating nitrogen species into sp2-hybridized carbon materials has proved an efficient means to improve their electrochemical performance. Nevertheless, an inevitable mixture of nitrogen species in carbon mate...
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Article
Open AccessPrefrontal reinstatement of contextual task demand is predicted by separable hippocampal patterns
Goal-directed behavior requires the representation of a task-set that defines the task-relevance of stimuli and guides stimulus-action map**s. Past experience provides one source of knowledge about likely ta...
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Open AccessEnhancing photoluminescence of carbon quantum dots doped PVA films with randomly dispersed silica microspheres
As a kind of excellent photoluminescent material, carbon quantum dots have been extensively studied in many fields, including biomedical applications and optoelectronic devices. They have been dispersed in pol...
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Article
Open AccessStrain-driven growth of ultra-long two-dimensional nano-channels
Lateral heterostructures of two-dimensional transition metal dichalcogenides (TMDs) have offered great opportunities in the engineering of monolayer electronics, catalysis and optoelectronics. To explore the f...
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Open AccessRetraction Note: Genetic regulation of salt stress tolerance revealed by RNA-Seq in cotton diploid wild species, Gossypium davidsonii
This article has been retracted.
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Open AccessIdentification on mitogen-activated protein kinase signaling cascades by integrating protein interaction with transcriptional profiling analysis in cotton
Plant mitogen-activated protein kinase (MAPK) cascades play important roles in development and stress responses. In previous studies, we have systematically investigated the mitogen-activated protein kinase ki...
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Open AccessGenome-wide identification and characterization of SPL transcription factor family and their evolution and expression profiling analysis in cotton
Plant specific transcription factors, SQUAMOSA promoter-binding protein-like (SPL), are involved in many biological processes. However, no systematical study has been reported in cotton. In this study, a total...
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Open AccessAnalysis of Combined Transcriptomes Identifies Gene Modules that Differentially Respond to Pathogenic Stimulation of Vascular Smooth Muscle and Endothelial Cells
Smooth muscle cells (SMCs) and endothelial cells (ECs) are vital cell types composing the vascular medial wall and the atheroprotective inner lining, respectively. Current treatments for cardiovascular disease...
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Open AccessThe Role of Personality and Subjective Exposure Experiences in Posttraumatic Stress Disorder and Depression Symptoms among Children Following Wenchuan Earthquake
This study aims to investigate the role of personality traits and subjective exposure experiences in posttraumatic stress disorder and depression symptoms. In Qingchuan, 21,652 children aged 7 to 15 years were...
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Open AccessCombined Therapy with Shock Wave and Retrograde Bone Marrow-Derived Cell Transplantation for Osteochondral Lesions of the Talus
Multiple treatment strategies have been developed for osteochondral lesions (OCLs) of the talus. The purpose of this retrospective study was to assess retrograde autologous bone marrow cell (BMC) transplantati...