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Open AccessOral pimonidazole unveils clinicopathologic and epigenetic features of hypoxic tumour aggressiveness in localized prostate cancer
Tumor hypoxia is associated with prostate cancer (PCa) treatment resistance and poor prognosis. Pimonidazole (PIMO) is an investigational hypoxia probe used in clinical trials. A better understanding of the cl...
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Erratum to: Efficient and stable perovskite solar cells by build-in π-columns and ionic interfaces in covalent organic frameworks
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Open AccessPrognostic value of ferritin in ASCT MM patients: integration with GEP models and ISS series systems
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Excitation-assisted pseudo-ferroelectric effect in ultrathin graphene/phosphorene heterostructure
Pseudo-ferroelectric transistors have attracted particular interest owing to their applications in the non-volatile memories and neuromorphic circuits; however, it remains to be explored in the limit of few-la...
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Trajectories of α-fetoprotein and unresectable hepatocellular carcinoma outcomes receiving atezolizumab plus bevacizumab: a secondary analysis of IMbrave150 study
α-fetoprotein (AFP) response has been demonstrated as a biomarker for unresectable hepatocellular carcinoma (uHCC) patients receiving immunotherapy, but its definition is still unclear. This exploratory study ...
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Role of electrodes in study of hydrovoltaic effects
The last decade has witnessed the emergence of hydrovoltaic technology, which can harvest electricity from different forms of water movement, such as raindrops, waves, flows, moisture, and natural evaporation....
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Efficient and stable perovskite solar cells by build-in π-columns and ionic interfaces in covalent organic frameworks
Perovskite solar cells (PSCs) have attracted much attention due to their rapidly increased power conversion efficiencies, however, their inherent poor long-term stability hinders their commercialization. The d...
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Lifting surface reconstruction of Au (100) by tellurium adsorption
The Au (100) surface has been a subject of intense studies due to excellent catalytic activities and its model character for surface science. However, the spontaneous surface reconstruction buries active Au (1...
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Ultralow friction of ion-containing water nanodroplets
We reveal the ultralow friction or superlubricity of water nanodroplets containing cations and anions on graphene substrates at high ion concentration by molecular dynamics simulations. When the ion concentrat...
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Open AccessAutomated quantitative assessment of pediatric blunt hepatic trauma by deep learning-based CT volumetry
To develop an end-to-end deep learning method for automated quantitative assessment of pediatric blunt hepatic trauma based on contrast-enhanced computed tomography (CT).
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Open AccessComprehensive and integrative analyses identify TYW5 as a schizophrenia risk gene
Identifying the causal genes at the risk loci and elucidating their roles in schizophrenia (SCZ) pathogenesis remain significant challenges. To explore risk variants associated with gene expression in the huma...
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Flexoelectricity enhanced water splitting and hydrogen evolution reaction on grain boundaries of monolayer transition metal dichalcogenides
Our extensive first-principles calculations reveal that the chemical activities of monolayer transition metal dichalcogenides (TMDs) MX2 (M = Mo or W, and X = Te, Se, or S) for water splitting and hydrogen evolut...
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Open AccessOne-year follow-up of chest CT findings in patients after SARS-CoV-2 infection
Knowledge about the 1-year outcome of COVID-19 is limited. The aim of this study was to follow-up and evaluate lung abnormalities on serial computed tomography (CT) scans in patients with COVID-19 after hospit...
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Strong electron-ion coupling in gradient halide perovskite heterojunction
The electron-ion coupling in iontronics has great significance and potential for energy conversion and storage devices. However, it is a substantial challenge to integrate iontronics into all-solid-state semic...
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Probing interactions at two-dimensional heterointerfaces by boron nitride-wrapped tip
Non-covalent interactions are important for two-dimensional heterointerfaces but challenged to be accurately determined, especially when the dielectric hexagonal boron nitride (BN) is involved. Here, we presen...
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Open AccessExpression of BAG1 is associated with prognosis in kidney renal clear cell carcinoma based on bioinformatics
BCL2 associated Athano-Gene 1 (BAG1) has been described to be involved in the development and progression of cancer. But the role of BAG1 in kidney renal clear cell carcinoma (KIRC) has remained largely unknown.
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Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips
The identification of prostate stem/progenitor cells and characterization of the prostate epithelial cell lineage hierarchy are critical for understanding prostate cancer initiation. Here, we characterized 35,...
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Double drumheadlike surface states in elemental group V nodal line semimetals
Drumheadlike surface states are typical characteristics in nodal line semimetals and bring varieties of unusual attractive properties. Here we demonstrate the double drumheadlike surface states in group V elem...
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Thiocoraline mediates drug resistance in MCF-7 cells via PI3K/Akt/BCRP signaling pathway
Thiocoraline, a depsipeptide bisintercalator with potent antitumor activity, was first isolated from marine actinomycete Micromonospora marina. It possesses an intense toxicity to MCF-7 cells at nanomolar concent...
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Three-layer phosphorene-metal interfaces
Phosphorene has attracted much attention recently as an alternative channel material in nanoscale electronic and optoelectronic devices due to its high carrier mobility and tunable direct bandgap. Compared wit...