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  1. Article

    Open Access

    Vγ9+Vδ2+ T cell control of Listeria monocytogenes growth in infected epithelial cells requires butyrophilin 3A genes

    Intracellular bacteria produce antigens, which serve as potent activators of γδ T cells. Phosphoantigens are presented via a complex of butyrophilins (BTN) to signal infection to human Vγ9+Vδ2+ T cells. Here, ...

    Katrin Fischer, Michaela Bradlerova, Thomas Decker, Verena Supper in Scientific Reports (2023)

  2. No Access

    Article

    RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics

    Boztug and colleagues identify an immunodeficient patient with a deficiency in the guanine-nucleotide-exchange factor RASGRP1. They find that human RASGRP1 is important for the function of T cells, B cells and...

    Elisabeth Salzer, Deniz Cagdas, Miroslav Hons, Emily M Mace in Nature Immunology (2016)