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Article
Open AccessChromosome-level genome assembly and annotation of eel goby (Odontamblyopus rebecca)
The eel gobies fascinate researchers with many important features, including its unique body structure, benthic lifestyle, and degenerated eyes. However, genome assembly and exploration of the unique genomic c...
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Article
Open AccessUltra-strong tungsten refractory high-entropy alloy via stepwise controllable coherent nanoprecipitations
High-performance refractory alloys with ultrahigh strength and ductility are in demand for a wide range of critical applications, such as plasma-facing components. However, it remains challenging to increase t...
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Article
Open AccessDirect synthesis of sila-benzoazoles through hydrosilylation and rearrangement cascade reaction of benzoazoles and silanes
Sila-isosteres have attracted increasing attention due to their potential application in a variety of fields and their different properties compared to their carbon-containing analogs. However, the preparation...
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Article
Open AccessThe multifaceted role of the SASP in atherosclerosis: from mechanisms to therapeutic opportunities
The global population of older individuals is growing, and ageing is a key risk factor for atherosclerotic cardiovascular diseases. Abnormal accumulation of senescent cells can cause potentially deleterious ef...
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Article
Open AccessParallel functional assessment of m6A sites in human endodermal differentiation with base editor screens
N6-methyladenosine (m6A) plays important role in lineage specifications of embryonic stem cells. However, it is still difficult to systematically dissect the specific m6A sites that are essential for early lineag...
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Article
Open AccessMD-SVM: a novel SVM-based algorithm for the motif discovery of transcription factor binding sites
Transcription factors (TFs) play important roles in the regulation of gene expression. They can activate or block transcription of downstream genes in a manner of binding to specific genomic sequences. Therefo...
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Article
Open AccessA new nanoscale metastable iron phase in carbon steels
Metastable ω phase is common in body-centred cubic (bcc) metals and alloys, including high-alloying steels. Recent theoretical calculations also suggest that the ω structure may act as an intermediate phase fo...