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  1. No Access

    Article

    A novel mechanism for the store-operated calcium influx pathway

    Activation of store-operated channels (SOCs) and capacitative calcium influx are triggered by depletion of intracellular calcium stores. However, the exact molecular mechanism of such communication remains unc...

    Tarik Smani, Sergey I. Zakharov, Peter Csutora, Endri Leno… in Nature Cell Biology (2004)

  2. Article

    Open Access

    Orai1α, but not Orai1β, co-localizes with TRPC1 and is required for its plasma membrane location and activation in HeLa cells

    The identification of two variants of the canonical pore-forming subunit of the Ca2+ release-activated Ca2+ (CRAC) channel Orai1, Orai1α and Orai1β, in mammalian cells arises the question whether they exhibit dif...

    Jose Sanchez-Collado, Jose J. Lopez, Isaac Jardin… in Cellular and Molecular Life Sciences (2022)

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