3 Result(s)
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Article
Surya Pandey
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Article
Open AccessUltrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas
Given the marginal penetration of most drugs across the blood-brain barrier, the efficacy of various agents remains limited for glioblastoma (GBM). Here we employ low-intensity pulsed ultrasound (LIPU) and int...
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Article
Open AccessA pairwise cytokine code explains the organism-wide response to sepsis
Sepsis is a systemic response to infection with life-threatening consequences. Our understanding of the molecular and cellular impact of sepsis across organs remains rudimentary. Here, we characterize the path...
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Article
A whole-tissue RNA-seq toolkit for organism-wide studies of gene expression with PME-seq
The immune system operates at the scale of the whole organism in mammals. We currently lack experimental approaches to systematically track and study organism-wide molecular processes in mice. Here we describe...
