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  1. No Access

    Article

    Comparative evaluation of canine cadaver embalming methods for veterinary anatomy education

    Formalin-embalmed cadavers have been extensively used to teach anatomy. Although they ensure the preservation of anatomical structures without microbial contamination, they are considerably rigid and cannot be...

    Sung Min Nam, Je-Sung Moon, Hun-Young Yoon… in Anatomical Science International (2020)

  2. No Access

    Article

    Phosphoglycerate Mutase 1 Promotes Cell Proliferation and Neuroblast Differentiation in the Dentate Gyrus by Facilitating the Phosphorylation of cAMP Response Element-Binding Protein

    In a previous study, we observed a significant increase in phosphoglycerate mutase 1 (PGAM1) levels after pyridoxine treatment. In the present study, we investigated the effects of PGAM1 on novel object recogn...

    Hyo Young Jung, Hyun Jung Kwon, Woosuk Kim, Sung Min Nam… in Neurochemical Research (2019)

  3. No Access

    Article

    Ultrastructural Changes and Expression of PCNA and RPE65 in Sodium Iodate-Induced Acute Retinal Pigment Epithelium Degeneration Model

    Alteration in retinal pigment epithelium (RPE) results in the visual dysfunction and blindness of retinal degenerative diseases. Injection of sodium iodate (NaIO3) generates degeneration of RPE. We analyzed the s...

    Hong-Lim Kim, Sung Min Nam, Byung-Joon Chang, Sang-Soep Nahm… in Neurochemical Research (2018)

  4. No Access

    Article

    Differential Effects of Low- and High-dose Zinc Supplementation on Synaptic Plasticity and Neurogenesis in the Hippocampus of Control and High-fat Diet-fed Mice

    In the present study, we investigated the concentration-dependent effect of zinc (Zn) supplementation on the adult hippocampus in a high-fat diet (HFD)-fed obese mouse model. Four-weeks after HFD- and control ...

    Sung Min Nam, Jong Whi Kim, Hyun Jung Kwon, Dae Young Yoo… in Neurochemical Research (2017)

  5. No Access

    Article

    Hairy and Enhancer of Split 6 (Hes6) Deficiency in Mouse Impairs Neuroblast Differentiation in Dentate Gyrus Without Affecting Cell Proliferation and Integration into Mature Neurons

    Hes6 is a member of the hairy-enhancer of split homolog (Hes) family of transcription factors and interacts with other Hes family genes. During development, Hes genes are expressed in neu...

    Sung Min Nam, Yo Na Kim, Jong Whi Kim… in Cellular and Molecular Neurobiology (2016)

  6. Article

    Open Access

    Physical exercise ameliorates the reduction of neural stem cell, cell proliferation and neuroblast differentiation in senescent mice induced by D-galactose

    Aging negatively affects adult hippocampal neurogenesis, and exercise attenuates the age-related reduction in adult hippocampal neurogenesis. In the present study, we used senescent mice induced by D-galactose...

    Sung Min Nam, Jong Whi Kim, Dae Young Yoo, Hee Sun Yim, Dae Won Kim… in BMC Neuroscience (2014)

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  7. No Access

    Article

    Comparison of N-Methyl-d-aspartate Receptor Subunit 1 and 4-Hydroxynonenal in the Hippocampus of Natural and Chemical-Induced Aging Accelerated Mice

    In this study, we compared N-methyl-d-aspartate receptor type 1 (NMDAR1) and 4-hydroxynonenal (4-HNE) in the hippocampus of d-galactose (d-gal)-induced and naturally aging models of mice. These markers represent...

    Sung Min Nam, Tae-Ho Chung, Jong Whi Kim, Hyo Young Jung… in Neurochemical Research (2014)

  8. No Access

    Article

    Tat-DJ-1 Protects Neurons from Ischemic Damage in the Ventral Horn of Rabbit Spinal Cord Via Increasing Antioxidant Levels

    The DJ-1 gene is highly conserved in diverse species and DJ-1 is known as an anti-oxidative stress factor. In this study, we investigated the neuroprotective effects of DJ-1 against ischemic damage in the rabb...

    Woosuk Kim, Dae Won Kim, Hoon Jae Jeong, Dae Young Yoo… in Neurochemical Research (2014)

  9. No Access

    Article

    Effects of Treadmill Exercise on Neural Stem Cells, Cell Proliferation, and Neuroblast Differentiation in the Subgranular Zone of the Dentate Gyrus in Cyclooxygenase-2 Knockout Mice

    Cyclooxygenase-2 (COX-2) function has been implicated in a number of physiological processes, including inflammatory responses, synaptic transmission, and synaptic plasticity in the brain. However, the specifi...

    Sung Min Nam, Jong Whi Kim, Dae Young Yoo, Jung Hoon Choi… in Neurochemical Research (2013)

  10. No Access

    Article

    Repeated Administration of PEP-1-Cu,Zn-Superoxide Dismutase and PEP-1-Peroxiredoxin-2 to Senescent Mice Induced by d-galactose Improves the Hippocampal Functions

    Oxidative stress initiates age-related reduction in hippocampal neurogenesis and the use of antioxidants has been proposed as an effective strategy to prevent or attenuate the reduction of neurogenesis in the ...

    Jung Hoon Choi, Dae Won Kim, Dae Young Yoo, Hoon Jae Jeong… in Neurochemical Research (2013)

  11. No Access

    Article

    Chronic Effects of Pyridoxine in the Gerbil Hippocampal CA1 Region after Transient Forebrain Ischemia

    In a previous study, we reported that the administration of pyridoxine (vitamin B6) to mice for 3 weeks significantly increased cell proliferation and neuroblast differentiation in the dentate gyrus without any n...

    Dae Young Yoo, Woosuk Kim, Sung Min Nam, ** Young Chung… in Neurochemical Research (2012)

  12. No Access

    Article

    Hypothyroid States Mitigate the Diabetes-Induced Reduction of Calbindin D-28k, Calretinin, and Parvalbumin Immunoreactivity in Type 2 Diabetic Rats

    In this study, we investigated the differences in calbindin D-28k (CB), calretinin, (CR) and parvalbumin (PV) immunoreactivity in the hippocampus of Zucker diabetic fatty (ZDF) rats and Zucker lean control (ZL...

    Sung Min Nam, Yo Na Kim, Dae Young Yoo, Sun Shin Yi, Woosuk Kim… in Neurochemical Research (2012)

  13. No Access

    Article

    Combination Effects of Sodium Butyrate and Pyridoxine Treatment on Cell Proliferation and Neuroblast Differentiation in the Dentate Gyrus of d-Galactose-Induced Aging Model Mice

    We previously reported that sodium butyrate (SB), a histone deacetylase inhibitor, robustly increased pyridoxine-induced cell proliferation and neuroblast differentiation in the dentate gyrus of the adult mous...

    Dae Young Yoo, Woosuk Kim, In Hye Kim, Sung Min Nam… in Neurochemical Research (2012)

  14. No Access

    Article

    Reduced Cell Proliferation and Neuroblast Differentiation in the Dentate Gyrus of High Fat Diet-Fed Mice are Ameliorated by Metformin and Glimepiride Treatment

    We investigated the effects of a high-fat diet (HFD) and the subsequent treatment of metformin (met) and glimepiride (glim), which are widely prescribed for type 2 diabetes, on cell proliferation and neuroblas...

    Dae Young Yoo, Woosuk Kim, Sung Min Nam, Ki-Yeon Yoo… in Neurochemical Research (2011)

  15. No Access

    Article

    PEP-1-Frataxin Significantly Increases Cell Proliferation and Neuroblast Differentiation by Reducing Lipid Peroxidation in the Mouse Dentate Gyrus

    Frataxin plays important roles in the mitochondrial respiratory chain and in the differentiation of neurons during early development. In this study, we observed the effects of frataxin on cell proliferation an...

    Woosuk Kim, Dae Won Kim, Bich Na Shin, Dae Young Yoo… in Neurochemical Research (2011)

  16. No Access

    Article

    Synergistic Effects of Sodium Butyrate, a Histone Deacetylase Inhibitor, on Increase of Neurogenesis Induced by Pyridoxine and Increase of Neural Proliferation in the Mouse Dentate Gyrus

    We previously observed that pyridoxine (vitamin B6) significantly increased cell proliferation and neuroblast differentiation without any neuronal damage in the hippocampus. In this study, we investigated the eff...

    Dae Young Yoo, Woosuk Kim, Sung Min Nam, Dae Won Kim… in Neurochemical Research (2011)

  17. No Access

    Article

    The Chronological Characteristics of SOD1 Activity and Inflammatory Response in the Hippocampi of STZ-Induced Type 1 Diabetic Rats

    Because it appears that oxidative stress and inflammation are implicated with disease pathogenesis in the diabetic brain, many researchers have used streptozotocin (STZ)-induced diabetic animals to study super...

    Sun Shin Yi, In Koo Hwang, Dae Won Kim, Jae Hoon Shin… in Neurochemical Research (2011)