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within Article Remove this filter Shadrielle Melijah G. Espiritu Remove this filter Biomedicine, general Remove this filter

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  1. No Access

    Article

    A community effort to create standards for evaluating tumor subclonal reconstruction

    Tumor DNA sequencing data can be interpreted by computational methods that analyze genomic heterogeneity to infer evolutionary dynamics. A growing number of studies have used these approaches to link cancer ev...

    Adriana Salcedo, Maxime Tarabichi, Shadrielle Melijah G. Espiritu… in Nature Biotechnology (2020)

  2. No Access

    Article

    Genome-wide germline correlates of the epigenetic landscape of prostate cancer

    Oncogenesis is driven by germline, environmental and stochastic factors. It is unknown how these interact to produce the molecular phenotypes of tumors. We therefore quantified the influence of germline polymo...

    Kathleen E. Houlahan, Yu-Jia Shiah, Alexander Gusev, Jiapei Yuan… in Nature Medicine (2019)