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Supplementation with antioxidant micronutrients in pregnant women with obesity: a randomized controlled trial
Obesity increases maternal morbidity and adversely affects child health. Maternal inflammation may play a role in adverse outcomes. The objective of this study was to determine whether providing a higher dose ...
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Article
Perinatal inflammation, fetal growth restriction, and long-term neurodevelopmental impairment in Bangladesh
There are limited data on the impact of perinatal inflammation on child neurodevelopment in low-middle income countries and among growth-restricted infants.
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Article
Lactoferrin intake from maternal milk during the neonatal hospitalization and early brain development among preterm infants
Lactoferrin is an immuno-modulatory nutrient in human milk that may be neuroprotective.
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Establishing a regional registry for neonatal encephalopathy: impact on identification of gaps in practice
Neonatal encephalopathy (NE) continues to be a significant risk for death and disability. To address this risk, regional guidelines were developed with the support of a malpractice insurance patient safety org...
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Article
Association of early cerebral oxygen saturation and brain injury in extremely preterm infants
To assess the association between cerebral saturation (crSO2) using Near-Infrared Spectroscopy (NIRS) and brain injury in extremely preterm infants.
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Blood gas measures as predictors for neonatal encephalopathy severity
To correlate arterial umbilical cord gas (aUCG) and infant blood gas with severity of neurological injury.
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Open AccessTargeting human milk fortification to improve very preterm infant growth and brain development: study protocol for Nourish, a single-center randomized, controlled clinical trial
Human milk is recommended for very preterm infants, but its variable macronutrient content may contribute to undernutrition during a critical period in development. We hypothesize that individually targeted hu...
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Open AccessA randomized controlled trial investigating the impact of maternal dietary supplementation with pomegranate juice on brain injury in infants with IUGR
Animal studies have demonstrated the therapeutic potential of polyphenol-rich pomegranate juice. We recently reported altered white matter microstructure and functional connectivity in the infant brain followi...
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Article
Maternal obesity and cesarean section delivery: additional risk factors for neonatal hypoglycemia?
To determine (1) whether higher maternal body mass index (BMI) and Cesarean (C) Section mode of delivery are associated with neonatal hypoglycemia (NH) and (2) whether timing of NH onset differs by risk factors.
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Article
Open AccessGestational cytokine concentrations and neurocognitive development at 7 years
Gestational inflammation may contribute to brain abnormalities associated with childhood neuropsychiatric disorders. Limited knowledge exists regarding the associations of maternal cytokine levels during pregn...
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Article
Cells in midline thalamus, central amygdala, and nucleus accumbens responding specifically to antipsychotic drugs
Determining brain regions in which neuroleptic drugs of different types produce similar effects, especially where these effects are not shared with drugs lacking antipsychotic efficacy, provides evidence as to...
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Article
Activation of midline thalamic nuclei by antipsychotic drugs
The thalamus has been proposed as a site which may be involved in the production of the syndrome of schizophrenia and the response of schizophrenic symptoms to treatment. These studies test whether, consistent...