![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
A Low-Cost IoT Architecture Based on LPWAN and MQTT for Monitoring Water Resources in Andean Wetlands
This paper describes the development of a monitoring system for water sources in the Tres Lagunas Andean high-altitude wetlands ecosystem (Ecuador), utilizing LoRa technology. The system design primarily invol...
-
Article
Open AccessAuthor Correction: The evolutionary history of 2,658 cancers
-
Article
Open AccessThe evolution of relapse of adult T cell acute lymphoblastic leukemia
Adult T cell acute lymphoblastic leukemia (T-ALL) is a rare disease that affects less than 10 individuals in one million. It has been less studied than its cognate pediatric malignancy, which is more prevalent...
-
Article
Author Correction: PGBD5 promotes site-specific oncogenic mutations in human tumors
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
-
Article
Pan-cancer computational histopathology reveals mutations, tumor composition and prognosis
We use deep transfer learning to quantify histopathological patterns across 17,355 hematoxylin and eosin-stained histopathology slide images from 28 cancer types and correlate these with matched genomic, trans...
-
Article
Open AccessMutational signatures are jointly shaped by DNA damage and repair
Cells possess an armamentarium of DNA repair pathways to counter DNA damage and prevent mutation. Here we use C. elegans whole genome sequencing to systematically quantify the contributions of these factors to mu...
-
Article
Open AccessThe evolutionary history of 2,658 cancers
Cancer develops through a process of somatic evolution1,2. Sequencing data from a single biopsy represent a snapshot of this process that can reveal the timing of specific genomic aberrations and the changing inf...
-
Article
Open AccessGenomic landscape and chronological reconstruction of driver events in multiple myeloma
The multiple myeloma (MM) genome is heterogeneous and evolves through preclinical and post-diagnosis phases. Here we report a catalog and hierarchy of driver lesions using sequences from 67 MM genomes serially...
-
Article
Ultrasound-assisted definition of inferior border of the trapezius muscle in lower trapezius island flap reconstruction
Utilization of lower trapezius island flap (LTIF) provides an alternative in reconstruction of the select defects in head and neck region. When muscle bulk is needed under the skin paddle, it may be important ...
-
Article
Erratum: PGBD5 promotes site-specific oncogenic mutations in human tumors
Nat. Genet.; doi:10.1038/ng.3866; corrected online 24 May 2017 In the version of this article initially published online, the affiliations for Jiali Zhuang listed an incorrect present address instead of an equ...
-
Article
PGBD5 promotes site-specific oncogenic mutations in human tumors
Alex Kentsis and colleagues identify somatic genomic rearrangements in primary human rhabdoid tumors characterized by deletions and inversions involving PGBD5-specific signal sequences at their breakpoints. Th...
-
Article
Non-coding recurrent mutations in chronic lymphocytic leukaemia
Chronic lymphocytic leukaemia (CLL) is a frequent disease in which the genetic alterations determining the clinicobiological behaviour are not fully understood. Here we describe a comprehensive evaluation of t...
-
Article
Deep carbon export from a Southern Ocean iron-fertilized diatom bloom
Fertilization of the ocean by adding iron compounds has induced diatom-dominated phytoplankton blooms accompanied by considerable carbon dioxide drawdown in the ocean surface layer. However, because the fate o...