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Richard J. Edwards
Microarrays
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Open AccessChromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome
Basenjis are considered an ancient dog breed of central African origins that still live and hunt with tribesmen in the African Congo. Nicknamed the barkless dog, Basenjis possess unique phylogeny, geographical...
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Open AccessTranscriptome analysis of human brain tissue identifies reduced expression of complement complex C1Q Genes in Rett syndrome
MECP2, the gene mutated in the majority of Rett syndrome cases, is a transcriptional regulator that can activate or repress transcription. Although the transcription regulatory function of MECP2 has been known...
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Open AccessEstimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated proteins
Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing methods for estimating the probability of mot...
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Open AccessGASP: Gapped Ancestral Sequence Prediction for proteins
The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a simple procedure and relies on accurate align...
