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  1. No Access

    Article

    Role of m6A modifications in immune evasion and immunotherapy

    RNA modification has garnered increasing attention in recent years due to its pivotal role in tumorigenesis and immune surveillance. N6-methyladenosine (m6A) modification is the most prevalent RNA modification, w...

    Chunyu Wu, Lvyuan Li, Qiling Tang, Qian** Liao, Pan Chen, Can Guo… in Medical Oncology (2024)

  2. Article

    Open Access

    Neoadjuvant nivolumab with or without platinum-doublet chemotherapy based on PD-L1 expression in resectable NSCLC (CTONG1804): a multicenter open-label phase II study

    This prospective multicenter phase II study evaluated the clinical efficacy of neoadjuvant nivolumab-exclusive (N) and nivolumab–chemotherapy (N/C) combinations based on PD-L1 expression. Eligible patients exh...

    Si-Yang Liu, Song Dong, Xue-Ning Yang… in Signal Transduction and Targeted Therapy (2023)

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  3. Article

    Open Access

    Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer: final overall survival analysis of the EMERGING-CTONG 1103 randomised phase II trial

    EMERGING-CTONG 1103 showed improved progression-free survival (PFS) with neoadjuvant erlotinib vs. chemotherapy for patients harbouring EGFR sensibility mutations and R0 resected stage IIIA-N2 non-small cell l...

    Wen-Zhao Zhong, Hong-Hong Yan, Ke-Neng Chen… in Signal Transduction and Targeted Therapy (2023)

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  4. Article

    Open Access

    SRC-3/TRAF4 facilitates ovarian cancer development by activating the PI3K/AKT signaling pathway

    Ovarian cancer is the seventh most common cancer in women, and it causes many deaths in women worldwide. Patients with ovarian cancer have a poor prognosis and low survival rate. This study aimed to explore th...

    Ying Wang, **a Luo, Nayiyuan Wu, Qian** Liao, **g Wang in Medical Oncology (2023)

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  5. Article

    Open Access

    Long non-coding RNA AFAP1-AS1 accelerates lung cancer cells migration and invasion by interacting with SNIP1 to upregulate c-Myc

    Actin filament associated protein 1 antisense RNA 1 (named AFAP1-AS1) is a long non-coding RNA and overexpressed in many cancers. This study aimed to identify the role and mechanism of AFAP1-AS1 in lung cancer...

    Yu Zhong, Liting Yang, Fang **ong, Yi He… in Signal Transduction and Targeted Therapy (2021)

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  6. No Access

    Article

    Prognostic value of Twist and E-cadherin in patients with osteosarcoma

    Twist, a basic helix-loop-helix transcription factor, and E-cadherin are both correlated with the metastatic progression of several types of cancer. However, it is currently unknown whether their activations h...

    Ke Yin, Qiande Liao, Hongbo He, Da Zhong in Medical Oncology (2012)