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Role of m6A modifications in immune evasion and immunotherapy

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  1. Article

    Open Access

    Neoadjuvant nivolumab with or without platinum-doublet chemotherapy based on PD-L1 expression in resectable NSCLC (CTONG1804): a multicenter open-label phase II study

    This prospective multicenter phase II study evaluated the clinical efficacy of neoadjuvant nivolumab-exclusive (N) and nivolumab–chemotherapy (N/C) combinations based on PD-L1 expression. Eligible patients exh...

    Si-Yang Liu, Song Dong, Xue-Ning Yang… in Signal Transduction and Targeted Therapy (2023)

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  2. Article

    Open Access

    Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer: final overall survival analysis of the EMERGING-CTONG 1103 randomised phase II trial

    EMERGING-CTONG 1103 showed improved progression-free survival (PFS) with neoadjuvant erlotinib vs. chemotherapy for patients harbouring EGFR sensibility mutations and R0 resected stage IIIA-N2 non-small cell l...

    Wen-Zhao Zhong, Hong-Hong Yan, Ke-Neng Chen… in Signal Transduction and Targeted Therapy (2023)

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  3. Article

    Open Access

    SRC-3/TRAF4 facilitates ovarian cancer development by activating the PI3K/AKT signaling pathway

    Ovarian cancer is the seventh most common cancer in women, and it causes many deaths in women worldwide. Patients with ovarian cancer have a poor prognosis and low survival rate. This study aimed to explore th...

    Ying Wang, **a Luo, Nayiyuan Wu, Qian** Liao, **g Wang in Medical Oncology (2023)

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  4. Article

    Open Access

    Long non-coding RNA AFAP1-AS1 accelerates lung cancer cells migration and invasion by interacting with SNIP1 to upregulate c-Myc

    Actin filament associated protein 1 antisense RNA 1 (named AFAP1-AS1) is a long non-coding RNA and overexpressed in many cancers. This study aimed to identify the role and mechanism of AFAP1-AS1 in lung cancer...

    Yu Zhong, Liting Yang, Fang **ong, Yi He… in Signal Transduction and Targeted Therapy (2021)

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